Reactome | phospho-p-CAMKK2 [nucleoplasm]

phospho-p-CAMKK2 [nucleoplasm]

Stable Identifier

R-DRE-9618968

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

nucleoplasm

Synonyms

E7FEF7

Locations in the PathwayBrowser

Expand all

Neuronal System (Danio rerio)

- Transmission across Chemical Synapses (Danio rerio)
  - Neurotransmitter receptors and postsynaptic signal transmission (Danio rerio)
    - Activation of NMDA receptors and postsynaptic events (Danio rerio)
      - Post NMDA receptor activation events (Danio rerio)
        
        CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde (Danio rerio)
        
        CaMKK autophosphorylates in the nucleus (Danio rerio)
        
        p-CaMKK:CALM1:4xCa2+ [nucleoplasm] (Danio rerio)
        
        phospho-p-CAMKK2 [nucleoplasm] (Danio rerio)

Signal Transduction (Danio rerio)

- Intracellular signaling by second messengers (Danio rerio)
  - DAG and IP3 signaling (Danio rerio)
    - CaM pathway (Danio rerio)
      - Calmodulin induced events (Danio rerio)
        
        CaMK IV-mediated phosphorylation of CREB (Danio rerio)
        
        CaMKK autophosphorylates in the nucleus (Danio rerio)
        
        p-CaMKK:CALM1:4xCa2+ [nucleoplasm] (Danio rerio)
        
        phospho-p-CAMKK2 [nucleoplasm] (Danio rerio)
- Signaling by GPCR (Danio rerio)
  - GPCR downstream signalling (Danio rerio)
    - G alpha (i) signalling events (Danio rerio)
      - Opioid Signalling (Danio rerio)
        
        G-protein mediated events (Danio rerio)
        
        PLC beta mediated events (Danio rerio)
        
        Ca-dependent events (Danio rerio)
        
        CaM pathway (Danio rerio)
        
        Calmodulin induced events (Danio rerio)
        
        CaMK IV-mediated phosphorylation of CREB (Danio rerio)
        
        CaMKK autophosphorylates in the nucleus (Danio rerio)
        
        p-CaMKK:CALM1:4xCa2+ [nucleoplasm] (Danio rerio)
        
        phospho-p-CAMKK2 [nucleoplasm] (Danio rerio)

External Reference Information

External Reference

UniProt:E7FEF7

Reference Genes

ENSEMBL:ENSDARG00000078645

ENSEMBL:ENSDARG00000078645.5

Other Identifiers

13108735

13288278

A_15_P256346

GO:0004672

GO:0005524

GO:0006468

GO:0016740

GO:0036211

GO:0140096

XM_687021

Participates

as a component of

p-CaMKK:CALM1:4xCa2+ [nucleoplasm] (Danio rerio)

Other forms of this molecule

CAMKK2 [cytosol]

phospho-p-CAMKK2 [cytosol]

CAMKK2 [nucleoplasm]

Inferred From

p-CaMKK [nucleoplasm] (Homo sapiens)

p-CAMKK2 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

phosphorylated residue at unknown position

PsiMod Name

phosphorylated residue [MOD:00696]

PsiMod Definition

A protein modification that effectively replaces a hydrogen atom with a phosphate group.

Cross References

ZFIN

ZDB-GENE-120215-179

Ensembl

ENSDARG00000078645, ENSDART00000114677, ENSDARP00000099148

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