Reactome | atp6v1d [cytosol]

atp6v1d [cytosol]

Stable Identifier

R-DRE-912597

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

ATP6V1D, Q7ZVX8

Locations in the PathwayBrowser

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Cellular responses to external stimuli (Danio rerio)

- Cellular responses to stress (Danio rerio)
  - Amino acids regulate mTORC1 (Danio rerio)
    - RRAGA,B exchanges GDP for GTP (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
    - RRAGA,B hydrolyzes GTP (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
    - RRAGC,D exchanges GTP for GDP (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
    - RRAGC,D hydrolyzes GTP (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
    - mTORC1 binds RHEB:GTP (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
    - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
    - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
    - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)

Signal Transduction (Danio rerio)

- Signaling by Receptor Tyrosine Kinases (Danio rerio)
  - Signaling by Insulin receptor (Danio rerio)
    - Insulin receptor recycling (Danio rerio)
      - ATP6AP1 binds V-ATPase (Danio rerio)
        
        V-ATPase [endosome membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Danio rerio)
        
        V-ATPase [endosome membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)
      - Endosome acidification (Danio rerio)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Danio rerio)
        
        V-ATPase [endosome membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1d [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:Q7ZVX8

Gene Names

atp6v1d

Reference Genes

BioGPS Gene:393935 atp6v1d

ENSEMBL:ENSDARG00000011175

KEGG Gene (Danio rerio):393935 atp6v1d

Monarch:393935 atp6v1d

NCBI Gene:393935 atp6v1d

Reference Transcript

RefSeq:NM_001167954.1 atp6v1d

Other Identifiers

13106393

393935

A_15_P185127

A_15_P301926

CUST_1106_PI428451958

DRER02995

Dr.14072.1.S1_at

ENSDART00000023488

ENSDART00000023488_1

ENSDART00000023488_2

GO:0003674

GO:0005575

GO:0006810

GO:0006811

GO:0008150

GO:0022857

GO:0032991

GO:0033176

GO:0042626

GO:0046961

GO:0055085

GO:1902600

GT_Spec_NM_001167954.1_38151

MADDr01009059

OTTDART00000023298

XM_682576

Participant Of

hasComponent

ATP6V1 [cytosol]

Other forms of this molecule

atp6v1d [plasma membrane]

atp6v1d [specific granule membrane]

Inferred From

ATP6V1D [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001161426.1

Ensembl

ENSDART00000023488, ENSDARP00000022320, ENSDARG00000011175

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