Reactome | atp6v1c1a [cytosol]

atp6v1c1a [cytosol]

Stable Identifier

R-DRE-912586

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

ATP6V1C1, Q7T385

Locations in the PathwayBrowser

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Cellular responses to stimuli (Danio rerio)

- Cellular responses to stress (Danio rerio)
  - Cellular response to starvation (Danio rerio)
    - Amino acids regulate mTORC1 (Danio rerio)
      - RRAGA,B exchanges GDP for GTP (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)
      - RRAGA,B hydrolyzes GTP (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)
      - RRAGC,D exchanges GTP for GDP (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)
      - RRAGC,D hydrolyzes GTP (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)
      - mTORC1 binds RHEB:GTP (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arginine dissociates yielding v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP and SLC38A9:Arginine (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)
      - v-ATPase:Ragulator:RagA,B:GDP:RagC,D:GDP binds SLC38A9:Arginine (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Danio rerio)
        
        v-ATPase:Ragulator [lysosomal membrane] (Danio rerio)
        
        v-ATPase [lysosomal membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)

Signal Transduction (Danio rerio)

- Signaling by Receptor Tyrosine Kinases (Danio rerio)
  - Signaling by Insulin receptor (Danio rerio)
    - Insulin receptor recycling (Danio rerio)
      - Endosome acidification (Danio rerio)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Danio rerio)
        
        V-ATPase [endosome membrane] (Danio rerio)
        
        ATP6V1 [cytosol] (Danio rerio)
        
        atp6v1c1a [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:Q7T385

Gene Names

atp6v1c1a

Reference Genes

BioGPS Gene:368907 atp6v1c1a

CTD Gene:368907 atp6v1c1a

ENSEMBL:ENSDARG00000023967

KEGG Gene (Danio rerio):368907 atp6v1c1a

Monarch:368907 atp6v1c1a

NCBI Gene:368907 atp6v1c1a

Reference Transcript

RefSeq:NM_201322.1 atp6v1c1a

Other Identifiers

13035164

368907

A_15_P109563

A_15_P119258

A_15_P628186

CUST_10179_PI428451958

DRER04014

DRER37528

Dr.14783.1.S1_at

ENSDART00000032275

ENSDART00000032275_1

ENSDART00000032275_2

GO:0005215

GO:0015078

GO:0033180

GO:0046961

GO:0055085

GO:0140657

GO:1902600

GT_Spec_NM_201322.1_319065

LOLS04069

MADDr01001547

NM_201322

Participates

as a component of

ATP6V1 [cytosol] (Danio rerio)

Inferred From

ATP6V1C [cytosol] (Homo sapiens)

ATP6V1C1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_958479.1

ZFIN

ZDB-GENE-030616-612

Ensembl

ENSDARP00000029343, ENSDARP00000147247, ENSDART00000191807, ENSDARG00000023967, ENSDART00000032275

PRO

Q7T385

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