Reactome | p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm]

p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm]

Stable Identifier

R-DRE-8949896

Type

Set [CandidateSet]

Species

Danio rerio

Compartment

nucleoplasm

Locations in the PathwayBrowser

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Participants

members

candidates

p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B [nucleoplasm] (Danio rerio)

Participates

as an output of

CDK4/6:CCND complexes are activated by T-loop phosphorylation of CDK4/6 (Danio rerio)

This entity regulates

Negatively

RB1 binds and inhibits E2F1/2/3:DP1/2 complexes (Danio rerio)

Inferred From

p-T172-CDK4,p-T177-CDK6:CCND:CDKN1A,CDKN1B,(CDKN1C); p-T172-CDK4,p-T177-CDK6:CCND; (p-T172-CDK4,p-T177-CDK6:CCND:p-Y88-CDKN1B) [nucleoplasm] (Homo sapiens)

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