Reactome | gpha2 [extracellular region]

gpha2 [extracellular region]

Stable Identifier

R-DRE-8942422

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

extracellular region

Synonyms

GPHA2, C6SUQ4

Locations in the PathwayBrowser

Expand all

Signal Transduction (Danio rerio)

- Signaling by GPCR (Danio rerio)
  - GPCR downstream signalling (Danio rerio)
    - G alpha (s) signalling events (Danio rerio)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Danio rerio)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Danio rerio)
        
        TSHR:Thyrotropin [plasma membrane] (Danio rerio)
        
        Thyrotropin, Thyrostimulin [extracellular region] (Danio rerio)
        
        Thyrostimulin [extracellular region] (Danio rerio)
        
        gpha2 [extracellular region] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Danio rerio)
        
        TSHR:Thyrotropin [plasma membrane] (Danio rerio)
        
        Thyrotropin, Thyrostimulin [extracellular region] (Danio rerio)
        
        Thyrostimulin [extracellular region] (Danio rerio)
        
        gpha2 [extracellular region] (Danio rerio)
  - GPCR ligand binding (Danio rerio)
    - Class A/1 (Rhodopsin-like receptors) (Danio rerio)
      - Hormone ligand-binding receptors (Danio rerio)
        
        Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin (Danio rerio)
        
        TSHR:Thyrotropin [plasma membrane] (Danio rerio)
        
        Thyrotropin, Thyrostimulin [extracellular region] (Danio rerio)
        
        Thyrostimulin [extracellular region] (Danio rerio)
        
        gpha2 [extracellular region] (Danio rerio)
        
        Thyrotropin, Thyrostimulin [extracellular region] (Danio rerio)
        
        Thyrostimulin [extracellular region] (Danio rerio)
        
        gpha2 [extracellular region] (Danio rerio)

External Reference Information

External Reference

UniProt:C6SUQ4

Gene Names

gpha2

Reference Genes

BioGPS Gene:100310882 gpha2

ENSEMBL:ENSDARG00000075403

ENSEMBL:ENSDARG00000115605 gpha2

KEGG Gene (Danio rerio):100310882 gpha2

Monarch:100310882 gpha2

NCBI Gene:100310882 gpha2

Reference Transcript

RefSeq:NM_001166684.1 gpha2

Other Identifiers

100310882

13236487

CUST_13370_PI428451958

DRER19230

ENSDART00000111619

GO:0003674

GO:0005179

GO:0005575

GO:0005576

GO:0005615

GO:0007165

GO:0007166

GO:0008150

GO:0051427

GT_Spec_NM_001166684.1_134026

GT_Spec_XM_005160925.1_383735

Participant Of

hasComponent

Thyrostimulin [extracellular region]

Inferred From

GPHA2 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_001160156.1

Ensembl

ENSDARG00000075403, ENSDART00000185950, ENSDARP00000103177, ENSDARP00000152870, ENSDARG00000115605, ENSDART00000111619

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