Reactome | gapvd1 [cytosol]

gapvd1 [cytosol]

Stable Identifier

R-DRE-8871123

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

GAPVD1, A0A2R8Q516

Locations in the PathwayBrowser

Expand all

Vesicle-mediated transport (Danio rerio)

- Membrane Trafficking (Danio rerio)
  - Clathrin-mediated endocytosis (Danio rerio)
    - Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Danio rerio)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Danio rerio)
        
        GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Danio rerio)
        
        gapvd1 [cytosol] (Danio rerio)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Danio rerio)
        
        GGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Danio rerio)
        
        gapvd1 [cytosol] (Danio rerio)
    - Dissociation of clathrin-associated proteins (Danio rerio)
      - GGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Danio rerio)
        
        gapvd1 [cytosol] (Danio rerio)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Danio rerio)
        
        GGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Danio rerio)
        
        gapvd1 [cytosol] (Danio rerio)
    - RAB5 and GAPVD1 bind AP-2 (Danio rerio)
      - GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Danio rerio)
        
        gapvd1 [cytosol] (Danio rerio)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Danio rerio)
        
        GGC-RAB5:GDP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Danio rerio)
        
        gapvd1 [cytosol] (Danio rerio)
  - Rab regulation of trafficking (Danio rerio)
    - RAB GEFs exchange GTP for GDP on RABs (Danio rerio)
      - RAB5 GEFs exchange GTP for GDP on RAB5 (Danio rerio)
        
        RAB5 GEFs [cytosol] (Danio rerio)
        
        gapvd1 [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:A0A2R8Q516

Gene Names

gapvd1

Reference Genes

BioGPS Gene:436693 gapvd1

ENSEMBL:ENSDARG00000090183

Monarch:436693 gapvd1

NCBI Gene:436693 gapvd1

Reference Transcript

RefSeq:XM_005167157.3 gapvd1

Other Identifiers

13254471

13274237

13287836

436693

A_15_P300156

CUST_22637_PI428451953

CUST_29606_PI428451953

CUST_8174_PI428451958

DRER12805

DRER19887

DRER20098

Dr.26138.1.A1_at

ENSDART00000085100

ENSDART00000112854

ENSDART00000113230

GO:0003674

GO:0005085

GO:0005575

GO:0006810

GO:0006897

GO:0007165

GO:0008150

GO:0016020

GO:0016192

GO:0019899

GO:0043087

GT_Xhyb_NM_001002420.2_155536

GT_Xhyb_XM_005167157.1_204805

GT_Xhyb_XM_005167158.1_204815

GT_Xhyb_XM_005167159.1_204795

MADDr01009368

NM_001002420

OTTDART00000028625

OTTDART00000028626

TC253024

XM_685551

Participant Of

hasComponent

hasMember

RAB5 GEFs [cytosol]

Inferred From

GAPVD1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_005167214.1

Ensembl

ENSDARG00000090183, ENSDARP00000148180, ENSDART00000180173

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