Reactome | s100b [extracellular region]

s100b [extracellular region]

Stable Identifier

R-DRE-879433

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

extracellular region

Synonyms

S100B, Q6DGT8

Locations in the PathwayBrowser

Expand all

Immune System (Danio rerio)

- Cytokine Signaling in Immune system (Danio rerio)
  - Signaling by Interleukins (Danio rerio)
    - Interleukin-1 family signaling (Danio rerio)
      - Interleukin-1 signaling (Danio rerio)
        
        TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
        
        NFkB complex is transported from cytosol to nucleus (Danio rerio)
        
        AGER ligands:AGER [plasma membrane] (Danio rerio)
        
        AGER ligands [extracellular region] (Danio rerio)
        
        S100B homodimer [extracellular region] (Danio rerio)
        
        s100b [extracellular region] (Danio rerio)
- Innate Immune System (Danio rerio)
  - Advanced glycosylation endproduct receptor signaling (Danio rerio)
    - Advanced glycosylation end product-specific receptor (AGER/RAGE) is a multiligand receptor (Danio rerio)
      - AGER ligands [extracellular region] (Danio rerio)
        
        S100B homodimer [extracellular region] (Danio rerio)
        
        s100b [extracellular region] (Danio rerio)
      - AGER ligands:AGER [plasma membrane] (Danio rerio)
        
        AGER ligands [extracellular region] (Danio rerio)
        
        S100B homodimer [extracellular region] (Danio rerio)
        
        s100b [extracellular region] (Danio rerio)
    - The TRTK-12 fragment of F-actin capping protein alpha binds the AGER ligand S100B (Danio rerio)
      - F-actin capping protein fragment TRTK12:S100B homodimer [extracellular region] (Danio rerio)
        
        S100B homodimer [extracellular region] (Danio rerio)
        
        s100b [extracellular region] (Danio rerio)
      - S100B homodimer [extracellular region] (Danio rerio)
        
        s100b [extracellular region] (Danio rerio)
  - DDX58/IFIH1-mediated induction of interferon-alpha/beta (Danio rerio)
    - TRAF6 mediated NF-kB activation (Danio rerio)
      - NFkB complex is transported from cytosol to nucleus (Danio rerio)
        
        AGER ligands:AGER [plasma membrane] (Danio rerio)
        
        AGER ligands [extracellular region] (Danio rerio)
        
        S100B homodimer [extracellular region] (Danio rerio)
        
        s100b [extracellular region] (Danio rerio)
  - Toll-like Receptor Cascades (Danio rerio)
    - Toll Like Receptor 10 (TLR10) Cascade (Danio rerio)
      - MyD88 cascade initiated on plasma membrane (Danio rerio)
        
        TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
        
        NFkB complex is transported from cytosol to nucleus (Danio rerio)
        
        AGER ligands:AGER [plasma membrane] (Danio rerio)
        
        AGER ligands [extracellular region] (Danio rerio)
        
        S100B homodimer [extracellular region] (Danio rerio)
        
        s100b [extracellular region] (Danio rerio)
    - Toll Like Receptor 2 (TLR2) Cascade (Danio rerio)
      - Toll Like Receptor TLR1:TLR2 Cascade (Danio rerio)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
        
        TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
        
        NFkB complex is transported from cytosol to nucleus (Danio rerio)
        
        AGER ligands:AGER [plasma membrane] (Danio rerio)
        
        AGER ligands [extracellular region] (Danio rerio)
        
        S100B homodimer [extracellular region] (Danio rerio)
        
        s100b [extracellular region] (Danio rerio)
      - Toll Like Receptor TLR6:TLR2 Cascade (Danio rerio)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
        
        TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
        
        NFkB complex is transported from cytosol to nucleus (Danio rerio)
        
        AGER ligands:AGER [plasma membrane] (Danio rerio)
        
        AGER ligands [extracellular region] (Danio rerio)
        
        S100B homodimer [extracellular region] (Danio rerio)
        
        s100b [extracellular region] (Danio rerio)
    - Toll Like Receptor 3 (TLR3) Cascade (Danio rerio)
      - TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
        
        NFkB complex is transported from cytosol to nucleus (Danio rerio)
        
        AGER ligands:AGER [plasma membrane] (Danio rerio)
        
        AGER ligands [extracellular region] (Danio rerio)
        
        S100B homodimer [extracellular region] (Danio rerio)
        
        s100b [extracellular region] (Danio rerio)
    - Toll Like Receptor 4 (TLR4) Cascade (Danio rerio)
      - MyD88-independent TLR4 cascade (Danio rerio)
        
        TRIF(TICAM1)-mediated TLR4 signaling (Danio rerio)
        
        TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
        
        NFkB complex is transported from cytosol to nucleus (Danio rerio)
        
        AGER ligands:AGER [plasma membrane] (Danio rerio)
        
        AGER ligands [extracellular region] (Danio rerio)
        
        S100B homodimer [extracellular region] (Danio rerio)
        
        s100b [extracellular region] (Danio rerio)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
        
        TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
        
        NFkB complex is transported from cytosol to nucleus (Danio rerio)
        
        AGER ligands:AGER [plasma membrane] (Danio rerio)
        
        AGER ligands [extracellular region] (Danio rerio)
        
        S100B homodimer [extracellular region] (Danio rerio)
        
        s100b [extracellular region] (Danio rerio)
    - Toll Like Receptor 5 (TLR5) Cascade (Danio rerio)
      - MyD88 cascade initiated on plasma membrane (Danio rerio)
        
        TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
        
        NFkB complex is transported from cytosol to nucleus (Danio rerio)
        
        AGER ligands:AGER [plasma membrane] (Danio rerio)
        
        AGER ligands [extracellular region] (Danio rerio)
        
        S100B homodimer [extracellular region] (Danio rerio)
        
        s100b [extracellular region] (Danio rerio)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Danio rerio)
      - MyD88 dependent cascade initiated on endosome (Danio rerio)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Danio rerio)
        
        TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
        
        NFkB complex is transported from cytosol to nucleus (Danio rerio)
        
        AGER ligands:AGER [plasma membrane] (Danio rerio)
        
        AGER ligands [extracellular region] (Danio rerio)
        
        S100B homodimer [extracellular region] (Danio rerio)
        
        s100b [extracellular region] (Danio rerio)
    - Toll Like Receptor 9 (TLR9) Cascade (Danio rerio)
      - MyD88 dependent cascade initiated on endosome (Danio rerio)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Danio rerio)
        
        TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Danio rerio)
        
        NFkB complex is transported from cytosol to nucleus (Danio rerio)
        
        AGER ligands:AGER [plasma membrane] (Danio rerio)
        
        AGER ligands [extracellular region] (Danio rerio)
        
        S100B homodimer [extracellular region] (Danio rerio)
        
        s100b [extracellular region] (Danio rerio)

External Reference Information

External Reference

UniProt:Q6DGT8

Gene Names

s100b

Reference Genes

BioGPS Gene:436825 s100b

ENSEMBL:ENSDARG00000057598

KEGG Gene (Danio rerio):436825 s100b

Monarch:436825 s100b

NCBI Gene:436825 s100b

Reference Transcript

Other Identifiers

13127141

13282424

436825

DRER11664

Dr.14787.1.A1_at

ENSDART00000080306

ENSDART00000080306_1

ENSDART00000080306_2

GO:0003674

GO:0005509

GO:0005575

GO:0005622

GO:0005634

GO:0005737

GO:0008270

GO:0043167

GO:0043226

GO:0046872

GT_Spec_NM_001002552.2_57491

LOLS14735

MADDr01005195

OTTDART00000011186

Participant Of

hasComponent

S100B homodimer [extracellular region]

Inferred From

S100B [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_001002552.1, XP_009294477.1

Ensembl

ENSDART00000080306, ENSDARP00000144602, ENSDARG00000057598, ENSDARP00000074756, ENSDART00000177971

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