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pik3cb [cytosol]
Stable Identifier
R-DRE-74788
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
cytosol
Synonyms
PIK3CB, E7F251
Locations in the PathwayBrowser
Expand all
Hemostasis (Danio rerio)
Cell surface interactions at the vascular wall (Danio rerio)
Tie2 Signaling (Danio rerio)
Interaction of Tie2 and p85 of PI3K (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
p85 bound to Tie2 [plasma membrane] (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
Platelet activation, signaling and aggregation (Danio rerio)
GPVI-mediated activation cascade (Danio rerio)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Danio rerio)
PI3K alpha, beta, gamma [cytosol] (Danio rerio)
PI3K beta [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
Immune System (Danio rerio)
Cytokine Signaling in Immune system (Danio rerio)
Signaling by Interleukins (Danio rerio)
Interleukin-3, Interleukin-5 and GM-CSF signaling (Danio rerio)
Regulation of signaling by CBL (Danio rerio)
CBL ubiquitinates PI3K (Danio rerio)
FYN-like kinases:p(Y731)-CBL:GRB2:Ubiquitinated p85-containing Class 1A PI3Ks [cytosol] (Danio rerio)
K63polyUb-p85-containing Class 1A PI3Ks [cytosol] (Danio rerio)
K63polyUb-PI3K beta [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
FYN-like kinases:p(Y731)-CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Danio rerio)
p85-containing Class 1A PI3Ks [cytosol] (Danio rerio)
PI3K beta [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
CBL, GRB2, FYN and PI3K p85 subunit are constitutively associated (Danio rerio)
FYN-like kinases:CBL:GRB2:p85-containing Class 1A PI3Ks [cytosol] (Danio rerio)
p85-containing Class 1A PI3Ks [cytosol] (Danio rerio)
PI3K beta [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
p85-containing Class 1A PI3Ks [cytosol] (Danio rerio)
PI3K beta [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
Metabolism (Danio rerio)
Metabolism of lipids (Danio rerio)
Phospholipid metabolism (Danio rerio)
PI Metabolism (Danio rerio)
Synthesis of PIPs at the plasma membrane (Danio rerio)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Danio rerio)
PIK3C(1) [cytosol] (Danio rerio)
PIK3CB:PIK3R1 [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
PIK3CB:PIK3R2 [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
PIK3CB:PIK3R3 [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Danio rerio)
PIK3(2) [cytosol] (Danio rerio)
PIK3CB:PIK3R1 [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
PIK3CB:PIK3R2 [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
PIK3CB:PIK3R3 [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
Signal Transduction (Danio rerio)
Intracellular signaling by second messengers (Danio rerio)
PIP3 activates AKT signaling (Danio rerio)
Negative regulation of the PI3K/AKT network (Danio rerio)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
Activator:PI3K [plasma membrane] (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK1/MAPK3 signaling (Danio rerio)
RAF/MAP kinase cascade (Danio rerio)
RAS:GTP binds PI3K (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
p21 RAS:GTP:PI3K [plasma membrane] (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by ALK (Danio rerio)
Active ALK recruits PI3K (Danio rerio)
Active ALK:PI3K [plasma membrane] (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
PI3K synthesizes PIP3 downstream of ALK (Danio rerio)
Active ALK:PI3K [plasma membrane] (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
Signaling by LTK (Danio rerio)
Active LTK receptor binds PI3K (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
p-5Y LTK dimer:ALKAL1,2:PI3K [plasma membrane] (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
Signaling by PDGF (Danio rerio)
Downstream signal transduction (Danio rerio)
PI3-kinase binds to the active receptor (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Danio rerio)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
Signaling by SCF-KIT (Danio rerio)
Synthesis of PIP3 from PIP2 by PI3K (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
Signaling by VEGF (Danio rerio)
VEGFA-VEGFR2 Pathway (Danio rerio)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K [plasma membrane] (Danio rerio)
PI3K [cytosol] (Danio rerio)
PI3K-catalytic subunit [cytosol] (Danio rerio)
pik3cb [cytosol] (Danio rerio)
External Reference Information
External Reference
UniProt:E7F251
Gene Names
pik3cb
Reference Genes
BioGPS Gene:100002263 pik3cb
ENSEMBL:ENSDARG00000075253
ENSEMBL:ENSDARG00000075253.5 pik3cb
KEGG Gene (Danio rerio):100002263 pik3cb
Monarch:100002263 pik3cb
NCBI Gene:100002263 pik3cb
Reference Transcript
RefSeq:XM_005157466.4 pik3cb
RefSeq:XM_001923222.6 pik3cb
Other Identifiers
100002263
13018476
A_15_P368575
A_15_P442710
A_15_P505402
A_15_P602317
A_15_P672451
CJ012414
CJ012428
CJ012703
CJ012729
CJ013264
CJ013282
CJ014495
CJ014515
CUST_1996_PI428451953
DRER20827
DRER53203
ENSDART00000114560
GO:0003824
GO:0005737
GO:0005886
GO:0005942
GO:0006629
GO:0016301
GO:0016303
GO:0016310
GO:0016740
GO:0023052
GO:0035005
GO:0036092
GO:0043491
GO:0046854
GO:0046934
GO:0048015
GT_Xhyb_XM_001923222.4_249895
GT_Xhyb_XM_005157466.1_249885
JP011531
LOLS15861
XM_694538
Participates
as a component of
K63polyUb-PI3K beta [cytosol] (Danio rerio)
PI3K beta [cytosol] (Danio rerio)
PIK3CB:PIK3R2 [cytosol] (Danio rerio)
PIK3CB:PIK3R1 [cytosol] (Danio rerio)
PIK3CB:PIK3R3 [cytosol] (Danio rerio)
as a member of
PI3K-catalytic subunit [cytosol] (Danio rerio)
Inferred From
PIK3CB [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_005157523.1
,
XP_001923257.4
ZFIN
ZDB-GENE-030131-1904
Ensembl
ENSDARP00000128403
,
ENSDART00000155268
,
ENSDARG00000075253
,
ENSDART00000114560
,
ENSDARP00000102724
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