Reactome | ice2 [nucleoplasm]

ice2 [nucleoplasm]

Stable Identifier

R-DRE-6807421

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

nucleoplasm

Synonyms

ICE2, A0A2R8QTY0

Locations in the PathwayBrowser

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Gene expression (Transcription) (Danio rerio)

- RNA Polymerase II Transcription (Danio rerio)
  - RNA polymerase II transcribes snRNA genes (Danio rerio)
    - Integrator complex processes the 3' end of snRNA (Danio rerio)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Danio rerio)
        
        LEC [nucleoplasm] (Danio rerio)
        
        ice2 [nucleoplasm] (Danio rerio)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Danio rerio)
        
        LEC [nucleoplasm] (Danio rerio)
        
        ice2 [nucleoplasm] (Danio rerio)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Danio rerio)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Danio rerio)
        
        LEC [nucleoplasm] (Danio rerio)
        
        ice2 [nucleoplasm] (Danio rerio)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Danio rerio)
        
        LEC [nucleoplasm] (Danio rerio)
        
        ice2 [nucleoplasm] (Danio rerio)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Danio rerio)
      - LEC [nucleoplasm] (Danio rerio)
        
        ice2 [nucleoplasm] (Danio rerio)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Danio rerio)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Danio rerio)
        
        LEC [nucleoplasm] (Danio rerio)
        
        ice2 [nucleoplasm] (Danio rerio)

External Reference Information

External Reference

UniProt:A0A2R8QTY0

Gene Names

ice2

Reference Genes

ENSEMBL:ENSDARG00000086670

Other Identifiers

100005372

13158077

A_15_P613002

BG883255_R

CUST_5276_PI428451953

DRER23707

Dr.16164.1.A1_at

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0008023

GO:0008150

GO:0009058

GO:0032991

GO:0034641

GO:0042795

GO:0042796

GO:0043226

GO:0045945

GT_Spec_XM_001344415.3_285985

XM_701239

Participant Of

hasComponent

LEC [nucleoplasm]

Inferred From

ICE2 [nucleoplasm] (Homo sapiens)

Cross References

Ensembl

ENSDART00000188515, ENSDARG00000086670, ENSDARP00000157333

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