Reactome | ndufs8 [mitochondrial matrix]

ndufs8 [mitochondrial matrix]

Stable Identifier

R-DRE-6788526

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

mitochondrial matrix

Synonyms

NDUFS8, Q6P0T0

Locations in the PathwayBrowser

Expand all

Metabolism (Danio rerio)

- Aerobic respiration and respiratory electron transport (Danio rerio)
  - Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Danio rerio)
    - Respiratory electron transport (Danio rerio)
      - Complex I biogenesis (Danio rerio)
        
        ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Danio rerio)
        
        550kDa complex [mitochondrial inner membrane] (Danio rerio)
        
        315kDa subcomplex [mitochondrial inner membrane] (Danio rerio)
        
        Intermediate 2 [mitochondrial inner membrane] (Danio rerio)
        
        Intermediate 1 [mitochondrial inner membrane] (Danio rerio)
        
        IP subcomplex [mitochondrial matrix] (Danio rerio)
        
        NDUFS8:2x4Fe-4S [mitochondrial matrix] (Danio rerio)
        
        ndufs8 [mitochondrial matrix] (Danio rerio)
        
        815kDa complex [mitochondrial inner membrane] (Danio rerio)
        
        550kDa complex [mitochondrial inner membrane] (Danio rerio)
        
        315kDa subcomplex [mitochondrial inner membrane] (Danio rerio)
        
        Intermediate 2 [mitochondrial inner membrane] (Danio rerio)
        
        Intermediate 1 [mitochondrial inner membrane] (Danio rerio)
        
        IP subcomplex [mitochondrial matrix] (Danio rerio)
        
        NDUFS8:2x4Fe-4S [mitochondrial matrix] (Danio rerio)
        
        ndufs8 [mitochondrial matrix] (Danio rerio)
        
        NUBPL transfers 4Fe-4S to Complex I subunits (Danio rerio)
        
        NDUFS8:2x4Fe-4S [mitochondrial matrix] (Danio rerio)
        
        ndufs8 [mitochondrial matrix] (Danio rerio)
        
        ndufs8 [mitochondrial matrix] (Danio rerio)
      - Complex I oxidises NADH to NAD+, reduces CoQ to QH2 (Danio rerio)
        
        Complex I [mitochondrial inner membrane] (Danio rerio)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Danio rerio)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Danio rerio)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Danio rerio)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Danio rerio)
        
        Intermediate 1 (-NDUFAF3,4,7, TIMMDC1) [mitochondrial inner membrane] (Danio rerio)
        
        NDUFS8:2x4Fe-4S [mitochondrial matrix] (Danio rerio)
        
        ndufs8 [mitochondrial matrix] (Danio rerio)

External Reference Information

External Reference

UniProt:Q6P0T0

Gene Names

ndufs8

Reference Genes

BioGPS Gene:406413 ndufs8

CTD Gene:406413 ndufs8

ENSEMBL:ENSDARG00000051986

ENSEMBL:ENSDARG00000051986.4 ndufs8

KEGG Gene (Danio rerio):406413 ndufs8

Monarch:406413 ndufs8

NCBI Gene:406413 ndufs8

Reference Transcript

RefSeq:NM_213139.1 ndufs8

Other Identifiers

12949449

406413

A_15_P205106

CUST_4659_PI428451958

DRER07900

Dr.2392.1.A1_at

ENSDART00000059227

ENSDART00000059227_1

ENSDART00000059227_2

GO:0003824

GO:0003954

GO:0005739

GO:0005747

GO:0006091

GO:0006120

GO:0007005

GO:0016020

GO:0016491

GO:0016651

GO:0032981

GO:0043226

GO:0051539

GO:0065003

GT_Spec_NM_213139.1_332525

MADDr01008801

NM_213139

OTTDART00000024102

Participates

as an input of

NUBPL transfers 4Fe-4S to Complex I subunits (Danio rerio)

as a component of

NDUFS8:2x4Fe-4S [mitochondrial matrix] (Danio rerio)

Inferred From

NDUF subunits [mitochondrial matrix] (Homo sapiens)

NDUFS8 [mitochondrial matrix] (Homo sapiens)

Cross References

RefSeq

NP_998304.1

ZFIN

ZDB-GENE-040426-2153

Ensembl

ENSDART00000059227, ENSDARP00000059226, ENSDARG00000051986