Reactome | phospho-il10ra [plasma membrane]

phospho-il10ra [plasma membrane]

Stable Identifier

R-DRE-6784793-2

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

plasma membrane

Synonyms

p-Y496-IL10RA, A0A0R4ITC2

Locations in the PathwayBrowser

Expand all

Immune System (Danio rerio)

- Cytokine Signaling in Immune system (Danio rerio)
  - Signaling by Interleukins (Danio rerio)
    - Interleukin-10 signaling (Danio rerio)
      - IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA [plasma membrane] (Danio rerio)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Danio rerio)
        
        phospho-il10ra [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA [plasma membrane] (Danio rerio)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Danio rerio)
        
        phospho-il10ra [plasma membrane] (Danio rerio)
      - STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA [plasma membrane] (Danio rerio)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Danio rerio)
        
        phospho-il10ra [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA [plasma membrane] (Danio rerio)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Danio rerio)
        
        phospho-il10ra [plasma membrane] (Danio rerio)
      - p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA [plasma membrane] (Danio rerio)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Danio rerio)
        
        phospho-il10ra [plasma membrane] (Danio rerio)
      - p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA [plasma membrane] (Danio rerio)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Danio rerio)
        
        phospho-il10ra [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA [plasma membrane] (Danio rerio)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Danio rerio)
        
        phospho-il10ra [plasma membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:A0A0R4ITC2

Gene Names

il10ra

Reference Genes

ENSEMBL:ENSDARG00000100383

Other Identifiers

13024204

777651

A_15_P178586

A_15_P196541

CJ001337

CJ001338

CUST_2410_PI428451953

CUST_9412_PI428451958

DRER08154

ENSDART00000060362

ENSDART00000060362_1

ENSDART00000060362_2

GO:0003674

GO:0004896

GO:0005515

GO:0005575

GO:0005886

GO:0006950

GO:0007165

GO:0007596

GO:0007599

GO:0008150

GO:0016020

GO:0016021

GO:0019221

GT_Spec_NM_001077625.1_139946

JP001337

JP001338

NM_001077625

Participant Of

hasMember

Homologues of p-Y496-IL10RA [plasma membrane]

Other forms of this molecule

phospho-il10ra [plasma membrane]

il10ra [extracellular region]

il10ra [plasma membrane]

phospho-il10ra [plasma membrane]

il10ra [plasma membrane]

phospho-il10ra [plasma membrane]

il10ra [plasma membrane]

Inferred From

p-Y496-IL10RA [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 496 (in Homo sapiens)

Coordinate

496

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

Ensembl

ENSDART00000170769, ENSDARG00000100383, ENSDARP00000138535

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