Reactome | phospho-crfb15 [plasma membrane]

phospho-crfb15 [plasma membrane]

Stable Identifier

R-DRE-6784793

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

plasma membrane

Synonyms

p-Y496-IL10RA, A0A0R4IAL7

Locations in the PathwayBrowser

Expand all

Immune System (Danio rerio)

- Cytokine Signaling in Immune system (Danio rerio)
  - Signaling by Interleukins (Danio rerio)
    - Interleukin-10 signaling (Danio rerio)
      - IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 binds STAT3 (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA [plasma membrane] (Danio rerio)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Danio rerio)
        
        phospho-crfb15 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA [plasma membrane] (Danio rerio)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Danio rerio)
        
        phospho-crfb15 [plasma membrane] (Danio rerio)
      - STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA [plasma membrane] (Danio rerio)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Danio rerio)
        
        phospho-crfb15 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA [plasma membrane] (Danio rerio)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Danio rerio)
        
        phospho-crfb15 [plasma membrane] (Danio rerio)
      - p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA [plasma membrane] (Danio rerio)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Danio rerio)
        
        phospho-crfb15 [plasma membrane] (Danio rerio)
      - p-Y705-STAT3 dissociates from IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA [plasma membrane] (Danio rerio)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Danio rerio)
        
        phospho-crfb15 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2 [plasma membrane] (Danio rerio)
        
        IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA:p-Y-JAK1 [plasma membrane] (Danio rerio)
        
        p-Y-IL10RA [plasma membrane] (Danio rerio)
        
        Homologues of p-Y496-IL10RA [plasma membrane] (Danio rerio)
        
        phospho-crfb15 [plasma membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:A0A0R4IAL7

Gene Names

crfb15

Reference Genes

ENSEMBL:ENSDARG00000099342

Other Identifiers

100535513

12953436

CJ001322

CUST_13246_PI428451953

DRER19103

DRER47975

ENSDART00000054875

GO:0003674

GO:0004896

GO:0005515

GO:0005575

GO:0005886

GO:0007165

GO:0008150

GO:0016020

GO:0016021

GO:0019221

GT_Spec_NM_001278848.1_422125

GT_Xhyb_XM_005170888.1_398295

JP001322

Participant Of

hasMember

Homologues of p-Y496-IL10RA [plasma membrane]

Other forms of this molecule

phospho-crfb15 [plasma membrane]

crfb15 [extracellular region]

crfb15 [plasma membrane]

phospho-crfb15 [plasma membrane]

crfb15 [plasma membrane]

phospho-crfb15 [plasma membrane]

crfb15 [plasma membrane]

Inferred From

p-Y496-IL10RA [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 496 (in Homo sapiens)

Coordinate

496

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

Ensembl

ENSDARG00000099342, ENSDART00000167452, ENSDARP00000131376

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