Reactome | uvssa [nucleoplasm]

uvssa [nucleoplasm]

Stable Identifier

R-DRE-5688915

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

nucleoplasm

Synonyms

UVSSA, E7EXT2

Locations in the PathwayBrowser

Expand all

DNA Repair (Danio rerio)

- Nucleotide Excision Repair (Danio rerio)
  - Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Danio rerio)
    - Dual incision in TC-NER (Danio rerio)
      - 5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Danio rerio)
        
        TC-NER incision complex [nucleoplasm] (Danio rerio)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
        
        UVSSA:USP7 [nucleoplasm] (Danio rerio)
        
        uvssa [nucleoplasm] (Danio rerio)
        
        TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
        
        UVSSA:USP7 [nucleoplasm] (Danio rerio)
        
        uvssa [nucleoplasm] (Danio rerio)
      - Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Danio rerio)
        
        TC-NER incision complex [nucleoplasm] (Danio rerio)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
        
        UVSSA:USP7 [nucleoplasm] (Danio rerio)
        
        uvssa [nucleoplasm] (Danio rerio)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
        
        UVSSA:USP7 [nucleoplasm] (Danio rerio)
        
        uvssa [nucleoplasm] (Danio rerio)
      - ERCC2-facilitated RNA Pol II backtracking in TC-NER (Danio rerio)
        
        TC-NER pre-incision complex [nucleoplasm] (Danio rerio)
        
        UVSSA:USP7 [nucleoplasm] (Danio rerio)
        
        uvssa [nucleoplasm] (Danio rerio)
        
        TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
        
        UVSSA:USP7 [nucleoplasm] (Danio rerio)
        
        uvssa [nucleoplasm] (Danio rerio)
      - ERCC3-facilitated RNA Pol II backtracking in TC-NER (Danio rerio)
        
        TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
        
        UVSSA:USP7 [nucleoplasm] (Danio rerio)
        
        uvssa [nucleoplasm] (Danio rerio)
        
        TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Danio rerio)
        
        UVSSA:USP7 [nucleoplasm] (Danio rerio)
        
        uvssa [nucleoplasm] (Danio rerio)
    - Formation of TC-NER Pre-Incision Complex (Danio rerio)
      - UVSSA:USP7 deubiquitinates ERCC6 (Danio rerio)
        
        TC-NER pre-incision complex [nucleoplasm] (Danio rerio)
        
        UVSSA:USP7 [nucleoplasm] (Danio rerio)
        
        uvssa [nucleoplasm] (Danio rerio)
        
        Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Danio rerio)
        
        UVSSA:USP7 [nucleoplasm] (Danio rerio)
        
        uvssa [nucleoplasm] (Danio rerio)

External Reference Information

External Reference

UniProt:E7EXT2

Gene Names

uvssa

Reference Genes

BioGPS Gene:402864 uvssa

ENSEMBL:ENSDARG00000100916

KEGG Gene (Danio rerio):402864 uvssa

Monarch:402864 uvssa

NCBI Gene:402864 uvssa

Reference Transcript

Other Identifiers

13014332

402864

CUST_4241_PI428451953

DRER23668

DRER28844

DRER40439

ENSDART00000017898

ENSDART00000017898_1

ENSDART00000017898_2

GO:0009411

GT_Xhyb_XM_005157206.1_65851

GT_Xhyb_XM_693180.4_35381

LOLS11380

XM_693180

Participates

as a component of

UVSSA:USP7 [nucleoplasm] (Danio rerio)

Inferred From

UVSSA [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_017214592.1, NP_001333081.1

ZFIN

ZDB-GENE-091204-111

Ensembl

ENSDARP00000133113, ENSDARP00000132945, ENSDART00000160677, ENSDART00000172666, ENSDARG00000100916

PRO

E7EXT2