Reactome | POLB:APEX1:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm]

POLB:APEX1:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm]

Stable Identifier

R-DRE-5649885

Type

Complex

Species

Danio rerio

Compartment

nucleoplasm

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

APEX1 [nucleoplasm] (Danio rerio)
Ghost homologue of SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Danio rerio)
POLB [nucleoplasm] (Danio rerio)

Participates

as an input of

PARP1,PARP2 dimers and FEN1 bind POLB and displace APEX1 from damaged AP site (Danio rerio)

as an output of

POLB incorporates the first 3' dNMP and displaces 5'ddRP at SSB site (Danio rerio)

Inferred From

POLB:APEX1:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Homo sapiens)

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