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derl2 [endoplasmic reticulum membrane]
Stable Identifier
R-DRE-5362350
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
endoplasmic reticulum membrane
Synonyms
DERL2, Q4VBS8
Locations in the PathwayBrowser
Expand all
Signal Transduction (Danio rerio)
Signaling by Hedgehog (Danio rerio)
Hedgehog ligand biogenesis (Danio rerio)
C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Danio rerio)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Danio rerio)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Danio rerio)
derl2 [endoplasmic reticulum membrane] (Danio rerio)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Danio rerio)
derl2 [endoplasmic reticulum membrane] (Danio rerio)
SYVN1 ubiquitinates Hh C-terminal fragments (Danio rerio)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Danio rerio)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Danio rerio)
derl2 [endoplasmic reticulum membrane] (Danio rerio)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Danio rerio)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Danio rerio)
derl2 [endoplasmic reticulum membrane] (Danio rerio)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Danio rerio)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Danio rerio)
derl2 [endoplasmic reticulum membrane] (Danio rerio)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Danio rerio)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Danio rerio)
derl2 [endoplasmic reticulum membrane] (Danio rerio)
Transport of small molecules (Danio rerio)
ABC-family proteins mediated transport (Danio rerio)
RNF5 and RNF185 ubiquitinate misfolded CFTR (Danio rerio)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Danio rerio)
ERAD complex [endoplasmic reticulum membrane] (Danio rerio)
DERL oligomer [endoplasmic reticulum membrane] (Danio rerio)
DERLs [endoplasmic reticulum membrane] (Danio rerio)
derl2 [endoplasmic reticulum membrane] (Danio rerio)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Danio rerio)
ERAD complex [endoplasmic reticulum membrane] (Danio rerio)
DERL oligomer [endoplasmic reticulum membrane] (Danio rerio)
DERLs [endoplasmic reticulum membrane] (Danio rerio)
derl2 [endoplasmic reticulum membrane] (Danio rerio)
External Reference Information
External Reference
UniProt:Q4VBS8
Gene Names
derl2
Reference Genes
BioGPS Gene:554093 derl2
ENSEMBL:ENSDARG00000042401
ENSEMBL:ENSDARG00000042401.7 derl2
KEGG Gene (Danio rerio):554093 derl2
Monarch:554093 derl2
NCBI Gene:554093 derl2
Reference Transcript
RefSeq:NM_001024395.1 derl2
Other Identifiers
13199051
554093
A_15_P119444
A_15_P164081
A_15_P707976
CJ011838
CJ011839
CJ011840
CUST_6020_PI428451958
DRER08495
Dr.20414.1.A1_s_at
ENSDART00000062175
ENSDART00000062175_1
ENSDART00000062175_2
GT_Spec_NM_001024395.1_231205
MADDr01002765
NM_001024395
ZV700S00003354
Participates
as a component of
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Danio rerio)
as a candidate of
DERLs [endoplasmic reticulum membrane] (Danio rerio)
Inferred From
DERL2 [endoplasmic reticulum membrane]
(Homo sapiens)
Cross References
RefSeq
NP_001019566.1
ZFIN
ZDB-GENE-050522-90
Ensembl
ENSDART00000062175
,
ENSDARP00000062174
,
ENSDARG00000042401
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