Reactome | h2ax [nucleoplasm]

h2ax [nucleoplasm]

Stable Identifier

R-DRE-5244606-2

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

nucleoplasm

Synonyms

MeR4-HIST1H2AH, Q7ZUY3

Locations in the PathwayBrowser

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Chromatin organization (Danio rerio)

- Chromatin modifying enzymes (Danio rerio)
  - RMTs methylate histone arginines (Danio rerio)
    - PRMT6 methylates arginine-4 of histone H2A (H2AR3) (Danio rerio)
      - Me2aR4-histone H2A, MeR4-histone H2A [nucleoplasm] (Danio rerio)
        
        MeR4-histone H2A [nucleoplasm] (Danio rerio)
        
        MeR4-histone HIST1H2A [nucleoplasm] (Danio rerio)
        
        Homologues of MeR4-HIST1H2AH [nucleoplasm] (Danio rerio)
        
        h2ax [nucleoplasm] (Danio rerio)
      - MeR4-histone H2A, Histone H2A [nucleoplasm] (Danio rerio)
        
        MeR4-histone H2A [nucleoplasm] (Danio rerio)
        
        MeR4-histone HIST1H2A [nucleoplasm] (Danio rerio)
        
        Homologues of MeR4-HIST1H2AH [nucleoplasm] (Danio rerio)
        
        h2ax [nucleoplasm] (Danio rerio)

External Reference Information

External Reference

UniProt:Q7ZUY3

Gene Names

h2ax

Reference Genes

BioGPS Gene:394048 h2ax

ENSEMBL:ENSDARG00000029406

KEGG Gene (Danio rerio):394048 h2ax

Monarch:394048 h2ax

NCBI Gene:394048 h2ax

Reference Transcript

RefSeq:NM_201073.1 h2ax

Other Identifiers

13205199

394048

A_15_P102171

A_15_P146346

DRER04841

Dr.17357.1.A1_at

ENSDART00000040328

ENSDART00000040328_y_1

ENSDART00000040328_y_2

GO:0000786

GO:0003677

GO:0005198

GO:0005622

GO:0005694

GO:0030527

GO:0032991

GO:0043226

GO:0046982

LOLS08211

MADDr01009168

OTTDART00000021591

Participates

as a member of

Homologues of MeR4-HIST1H2AH [nucleoplasm] (Danio rerio)

Other forms of this molecule

h2ax [nucleoplasm]

Inferred From

MeR4-HIST1H2AH [nucleoplasm] (Homo sapiens)

MeR4-HIST1H2AJ [nucleoplasm] (Homo sapiens)

Modified Residues

Name

omega-N-methyl-L-arginine at 4 (in Homo sapiens)

Coordinate

PsiMod Name

omega-N-methyl-L-arginine

PsiMod Definition

A protein modification that effectively converts an L-arginine residue to N(omega)-methyl-L-arginine.

Cross References

RefSeq

NP_957367.1

ZFIN

ZDB-GENE-040426-987

Ensembl

ENSDARP00000040327, ENSDART00000040328, ENSDARG00000029406

PRO

Q7ZUY3

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