Reactome | VAV3 [cytosol]

VAV3 [cytosol]

Stable Identifier

R-DRE-430152

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

B0S6C8

Locations in the PathwayBrowser

Expand all

Immune System (Danio rerio)

- Innate Immune System (Danio rerio)
  - DAP12 interactions (Danio rerio)
    - DAP12 signaling (Danio rerio)
      - Phosphorylation of PLC-gamma by p-BTK/p-SYK (Danio rerio)
        
        p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane] (Danio rerio)
        
        VAV1,2,3 [cytosol] (Danio rerio)
        
        VAV3 [cytosol] (Danio rerio)
        
        p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG [plasma membrane] (Danio rerio)
        
        VAV1,2,3 [cytosol] (Danio rerio)
        
        VAV3 [cytosol] (Danio rerio)
      - Release of p-PLCG1 (Danio rerio)
        
        p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV [plasma membrane] (Danio rerio)
        
        VAV1,2,3 [cytosol] (Danio rerio)
        
        VAV3 [cytosol] (Danio rerio)
        
        p-5Y-LAT:GRB2:SOS:GADS:p-3Y-SLP-76:p-2Y-BTK:VAV:p-PLCG [plasma membrane] (Danio rerio)
        
        VAV1,2,3 [cytosol] (Danio rerio)
        
        VAV3 [cytosol] (Danio rerio)
  - Fc epsilon receptor (FCERI) signaling (Danio rerio)
    - FCERI mediated Ca+2 mobilization (Danio rerio)
      - Autophosphorylation of BTK/ITK (Danio rerio)
        
        p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-TEC kinases [plasma membrane] (Danio rerio)
        
        VAV1,2,3 [cytosol] (Danio rerio)
        
        VAV3 [cytosol] (Danio rerio)
        
        p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane] (Danio rerio)
        
        VAV1,2,3 [cytosol] (Danio rerio)
        
        VAV3 [cytosol] (Danio rerio)
      - Hydrolysis of PIP2 by PLCG (Danio rerio)
        
        p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-2Y-BTK/p-2Y-ITK:PIP3 [plasma membrane] (Danio rerio)
        
        VAV1,2,3 [cytosol] (Danio rerio)
        
        VAV3 [cytosol] (Danio rerio)
      - Phosphorylation of TEC kinases by p-SYK (Danio rerio)
        
        p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:TEC kinases:PIP3 [plasma membrane] (Danio rerio)
        
        VAV1,2,3 [cytosol] (Danio rerio)
        
        VAV3 [cytosol] (Danio rerio)
        
        p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:p-TEC kinases:PIP3 [plasma membrane] (Danio rerio)
        
        VAV1,2,3 [cytosol] (Danio rerio)
        
        VAV3 [cytosol] (Danio rerio)
    - FCERI mediated MAPK activation (Danio rerio)
      - Phosphorylation and activation of VAV (Danio rerio)
        
        p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV [plasma membrane] (Danio rerio)
        
        VAV1,2,3 [cytosol] (Danio rerio)
        
        VAV3 [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:B0S6C8

Reference Genes

ENSEMBL:ENSDARG00000075962

ENSEMBL:ENSDARG00000075962.6

Other Identifiers

13087538

559145

A_15_P630371

CJ006476

CJ006509

CJ006608

CJ007182

CJ007230

CJ010072

CJ010525

CJ012780

CJ013667

CJ014098

DRER18343

Dr.10031.1.A1_at

ENSDART00000110059

GO:0005085

GO:0005515

GO:0023052

GO:0035556

GO:0098772

GT_Spec_XM_005163323.1_190525

JP006874

JP006907

JP007006

JP007580

JP007628

JP010470

JP010923

JP011588

MADDr01013582

Participates

as a member of

as a candidate of

Other forms of this molecule

phospho-p-Y173-VAV3 [cytosol]

Inferred From

VAV3 [cytosol] (Homo sapiens)

Cross References

ZFIN

ZDB-GENE-070912-251

Ensembl

ENSDART00000110059, ENSDARG00000075962, ENSDARP00000099666

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