Reactome | si:dkey-52h10.3 [plasma membrane]

si:dkey-52h10.3 [plasma membrane]

Stable Identifier

R-DRE-420574

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

plasma membrane

Synonyms

GRM6, A0A0R4IRN2

Locations in the PathwayBrowser

Expand all

Signal Transduction (Danio rerio)

- Signaling by GPCR (Danio rerio)
  - GPCR downstream signalling (Danio rerio)
    - G alpha (i) signalling events (Danio rerio)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Danio rerio)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Danio rerio)
        
        si:dkey-52h10.3 [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
        
        Group II and III metabotropic gutamate receptors:Glu [plasma membrane] (Danio rerio)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Danio rerio)
        
        si:dkey-52h10.3 [plasma membrane] (Danio rerio)
  - GPCR ligand binding (Danio rerio)
    - Class C/3 (Metabotropic glutamate/pheromone receptors) (Danio rerio)
      - Metabotropic glutamate receptors bind glutamate (Danio rerio)
        
        GRM1-8 [plasma membrane] (Danio rerio)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Danio rerio)
        
        si:dkey-52h10.3 [plasma membrane] (Danio rerio)
        
        GRM1-8:L-Glu [plasma membrane] (Danio rerio)
        
        GRM1-8 [plasma membrane] (Danio rerio)
        
        GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Danio rerio)
        
        si:dkey-52h10.3 [plasma membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:A0A0R4IRN2

Gene Names

si:dkey-52h10.3

Reference Genes

ENSEMBL:ENSDARG00000017742

Reference Transcript

RefSeq:XM_021478291.1 si:dkey-52h10.3

Other Identifiers

13243240

568484

A_15_P188871

A_15_P352200

CUST_10070_PI428451953

CUST_12492_PI428451958

DRER01600

DRER37981

ENSDART00000013311

ENSDART00000013311_1

ENSDART00000013311_2

GO:0001640

GO:0004930

GO:0005886

GO:0007154

GO:0007165

GO:0007186

GO:0007196

GO:0007216

GO:0016020

GO:0016021

GO:0023052

GO:0051966

GO:0060089

GT_Xhyb_NM_001123292.1_98911

XM_691814

Participates

as a member of

GRM2,GRM3,GRM4,GRM6,GRM7,GRM8 [plasma membrane] (Danio rerio)

Inferred From

GRM6 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_021333966.1

ZFIN

ZDB-GENE-060208-1

Ensembl

ENSDARG00000017742, ENSDARP00000139128, ENSDART00000169276

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