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phospho-p-Y590,Y596-EPHB4 [plasma membrane]
Stable Identifier
R-DRE-3928364
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
plasma membrane
Synonyms
O73875
Locations in the PathwayBrowser
Expand all
Developmental Biology (Danio rerio)
Nervous system development (Danio rerio)
Axon guidance (Danio rerio)
EPH-Ephrin signaling (Danio rerio)
EPH receptors autophosphorylate (Danio rerio)
p-EPH:ephrin oligomers [plasma membrane] (Danio rerio)
p-EPHB:EFNB oligomers [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs [plasma membrane] (Danio rerio)
phospho-p-Y590,Y596-EPHB4 [plasma membrane] (Danio rerio)
EPH-ephrin mediated repulsion of cells (Danio rerio)
SFKs phosphorylate VAV2,3 (Danio rerio)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane] (Danio rerio)
p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Danio rerio)
p-EPH:ephrin oligomers [plasma membrane] (Danio rerio)
p-EPHB:EFNB oligomers [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs [plasma membrane] (Danio rerio)
phospho-p-Y590,Y596-EPHB4 [plasma membrane] (Danio rerio)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Danio rerio)
p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Danio rerio)
p-EPH:ephrin oligomers [plasma membrane] (Danio rerio)
p-EPHB:EFNB oligomers [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs [plasma membrane] (Danio rerio)
phospho-p-Y590,Y596-EPHB4 [plasma membrane] (Danio rerio)
VAV exchanges GTP for GDP on RAC1, activating it (Danio rerio)
EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:p-VAV2,VAV3 [plasma membrane] (Danio rerio)
p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] (Danio rerio)
p-EPH:ephrin oligomers [plasma membrane] (Danio rerio)
p-EPHB:EFNB oligomers [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs [plasma membrane] (Danio rerio)
phospho-p-Y590,Y596-EPHB4 [plasma membrane] (Danio rerio)
EPHB-mediated forward signaling (Danio rerio)
CDC42 and PIP2 bind WASL, activating it (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP [plasma membrane] (Danio rerio)
p-EPHB:EFNB oligomers [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs [plasma membrane] (Danio rerio)
phospho-p-Y590,Y596-EPHB4 [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP [plasma membrane] (Danio rerio)
p-EPHB:EFNB oligomers [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs [plasma membrane] (Danio rerio)
phospho-p-Y590,Y596-EPHB4 [plasma membrane] (Danio rerio)
N-WASP binds ARP2/3 and G-actin (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP [plasma membrane] (Danio rerio)
p-EPHB:EFNB oligomers [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs [plasma membrane] (Danio rerio)
phospho-p-Y590,Y596-EPHB4 [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2 [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:ITSN1:N-WASP [plasma membrane] (Danio rerio)
p-EPHB:EFNB oligomers [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs [plasma membrane] (Danio rerio)
phospho-p-Y590,Y596-EPHB4 [plasma membrane] (Danio rerio)
Ras:GTP binds p120-RasGAP (Danio rerio)
p-EPHBs:EFNBs:RASA1 [plasma membrane] (Danio rerio)
p-EPHB:EFNB oligomers [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs [plasma membrane] (Danio rerio)
phospho-p-Y590,Y596-EPHB4 [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:RASA1:HRAS:GTP [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:RASA1 [plasma membrane] (Danio rerio)
p-EPHB:EFNB oligomers [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs [plasma membrane] (Danio rerio)
phospho-p-Y590,Y596-EPHB4 [plasma membrane] (Danio rerio)
p-EPHB phosphorylates SDC2 (Danio rerio)
p-EPHB:EFNB oligomers [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs [plasma membrane] (Danio rerio)
phospho-p-Y590,Y596-EPHB4 [plasma membrane] (Danio rerio)
p120-RasGAP activates GTP hydrolysis on RAS, inactivating it (Danio rerio)
p-EPHBs:EFNBs:RASA1:HRAS:GDP [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:RASA1 [plasma membrane] (Danio rerio)
p-EPHB:EFNB oligomers [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs [plasma membrane] (Danio rerio)
phospho-p-Y590,Y596-EPHB4 [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:RASA1:HRAS:GTP [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs:RASA1 [plasma membrane] (Danio rerio)
p-EPHB:EFNB oligomers [plasma membrane] (Danio rerio)
p-EPHBs:EFNBs [plasma membrane] (Danio rerio)
phospho-p-Y590,Y596-EPHB4 [plasma membrane] (Danio rerio)
External Reference Information
External Reference
UniProt:O73875
Reference Genes
BioGPS Gene:30688
CTD Gene:30688
ENSEMBL:ENSDARG00000100725
KEGG:dre:30688
Monarch:30688
NCBI Gene:30688
UCSC:O73875
Reference Transcript
RefSeq:NM_131414.1
Other Identifiers
13200394
30688
A_15_P119449
A_15_P461795
CUST_28881_PI428451953
CUST_28882_PI428451953
CUST_28883_PI428451953
CUST_28884_PI428451953
CUST_529_PI428451958
DRER24035
DRER28255
DRER32661
Dr.22293.1.A1_at
Dr.23044.1.A1_at
Dr.5764.1.S1_at
ENSDART00000059042
ENSDART00000059042_1
ENSDART00000059042_2
GO:0001525
GO:0001568
GO:0001945
GO:0003824
GO:0004713
GO:0004714
GO:0005003
GO:0005515
GO:0005524
GO:0005886
GO:0007169
GO:0009653
GO:0016740
GO:0035475
GO:0043235
GO:0048013
GO:0048845
GO:0048856
GO:0048870
GO:0060026
GO:0060089
GO:0140096
GT_Spec_NM_131414.1_303465
LOLS00543
LOLS01709
MADDr01002580
NM_001089449
TC244645
ZV700S00003739
ZV700S00003867
ZV700S00005725
Participates
as a component of
p-EPHBs:EFNBs [plasma membrane] (Danio rerio)
Other forms of this molecule
O73875 [plasma membrane]
EPHB4 (?-987) [cytosol]
EPHB4 (?-987) [plasma membrane]
EPHB4 (16-?) [extracellular region]
EPHB4 [plasma membrane]
Inferred From
p-EPHBs [plasma membrane]
(Homo sapiens)
p-Y590,Y596-EPHB4 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O4'-phospho-L-tyrosine at 590 (in Homo sapiens)
Coordinate
590
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 596 (in Homo sapiens)
Coordinate
596
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
ENSEMBL
ENSDARP00000152897
,
ENSDARG00000100725
,
ENSDART00000187955
ZFIN
ZDB-GENE-990415-62
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