Reactome | npffr2a [plasma membrane]

npffr2a [plasma membrane]

Stable Identifier

R-DRE-389476

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

plasma membrane

Synonyms

NPFFR2, A2AV71

Locations in the PathwayBrowser

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Signal Transduction (Danio rerio)

- Signaling by GPCR (Danio rerio)
  - GPCR downstream signalling (Danio rerio)
    - G alpha (q) signalling events (Danio rerio)
      - Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Danio rerio)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Danio rerio)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Danio rerio)
        
        npffr2a [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Danio rerio)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Danio rerio)
        
        npffr2a [plasma membrane] (Danio rerio)
  - GPCR ligand binding (Danio rerio)
    - Class A/1 (Rhodopsin-like receptors) (Danio rerio)
      - Peptide ligand-binding receptors (Danio rerio)
        
        Orexin and neuropeptides FF and QRFP bind to their respective receptors (Danio rerio)
        
        Two NPFF receptors can bind neuropeptide FF (Danio rerio)
        
        NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Danio rerio)
        
        npffr2a [plasma membrane] (Danio rerio)
        
        npffr2a [plasma membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:A2AV71

Gene Names

npffr2a

Reference Genes

BioGPS Gene:560955 npffr2a

CTD Gene:560955 npffr2a

ENSEMBL:ENSDARG00000033635.8

ENSEMBL:ENSDARG00000112567.1 npffr2a

ENSEMBL:ENSDARG00000116027.1 npffr2a

KEGG Gene (Danio rerio):560955 npffr2a

Monarch:560955 npffr2a

NCBI Gene:560955 npffr2a

Reference Transcript

Other Identifiers

13207475

560955

A_15_P146938

A_15_P372927

CUST_3400_PI428451958

DRER14492

ENSDART00000040751_y_1

ENSDART00000040751_y_2

ENSDART00000097645_y_1

ENSDART00000097645_y_2

ENSDART00000097646

GO:0004930

GO:0005886

GO:0007165

GO:0007186

GO:0007218

GO:0008188

GO:0016020

GO:0016021

GO:0023052

GO:0031628

GO:0032870

GO:0036211

GO:0042277

GO:0043408

GO:0045761

GO:0060089

GO:2000479

GT_Xhyb_NM_001105109.1_260985

MADDr01014774

OTTDART00000022542

OTTDART00000032571

XM_684353

XM_688088

Participates

as an input of

Two NPFF receptors can bind neuropeptide FF (Danio rerio)

as a component of

NPFFR1,NPFFR2:NPFF(69-76) [plasma membrane] (Danio rerio)

Inferred From

NPFFR1,NPFFR2 [plasma membrane] (Homo sapiens)

NPFFR2 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

XP_005165383.1, NP_001098579.1

ZFIN

ZDB-GENE-060526-183

Ensembl

ENSDART00000097645, ENSDARP00000151644, ENSDARP00000141745, ENSDART00000193659, ENSDARG00000033635, ENSDARG00000116027, ENSDARP00000157605, ENSDART00000168534, ENSDARG00000112567, ENSDART00000183018, ENSDARP00000088415

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