Reactome | cxcl8b.3 [extracellular region]

cxcl8b.3 [extracellular region]

Stable Identifier

R-DRE-373784-2

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

extracellular region

Synonyms

CXCL6(38-114), A0A0R4IPQ6

Locations in the PathwayBrowser

Expand all

Signal Transduction (Danio rerio)

- Signaling by GPCR (Danio rerio)
  - GPCR downstream signalling (Danio rerio)
    - G alpha (i) signalling events (Danio rerio)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
        
        CXCR1:CXCR1 ligands [plasma membrane] (Danio rerio)
        
        CXCR1 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Danio rerio)
        
        CXCR2 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
        
        CXCR1:CXCR1 ligands [plasma membrane] (Danio rerio)
        
        CXCR1 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Danio rerio)
        
        CXCR2 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
        
        CXCR1:CXCR1 ligands [plasma membrane] (Danio rerio)
        
        CXCR1 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Danio rerio)
        
        CXCR2 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
        
        CXCR1:CXCR1 ligands [plasma membrane] (Danio rerio)
        
        CXCR1 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Danio rerio)
        
        CXCR2 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)
      - The Ligand:GPCR:Gi complex dissociates (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
        
        CXCR1:CXCR1 ligands [plasma membrane] (Danio rerio)
        
        CXCR1 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Danio rerio)
        
        CXCR2 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
        
        CXCR1:CXCR1 ligands [plasma membrane] (Danio rerio)
        
        CXCR1 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Danio rerio)
        
        CXCR2 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)
  - GPCR ligand binding (Danio rerio)
    - Class A/1 (Rhodopsin-like receptors) (Danio rerio)
      - Peptide ligand-binding receptors (Danio rerio)
        
        Chemokine receptors bind chemokines (Danio rerio)
        
        Receptor CXCR1 binds CXCL6 and CXCL8 ligands (Danio rerio)
        
        CXCR1 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)
        
        CXCR1:CXCR1 ligands [plasma membrane] (Danio rerio)
        
        CXCR1 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)
        
        Receptor CXCR2 binds ligands CXCL1 to 7 (Danio rerio)
        
        CXCR2 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)
        
        CXCR2:CXCR2 ligands [plasma membrane] (Danio rerio)
        
        CXCR2 ligands [extracellular region] (Danio rerio)
        
        Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)
        
        cxcl8b.3 [extracellular region] (Danio rerio)

External Reference Information

External Reference

UniProt:A0A0R4IPQ6

Gene Names

cxcl8b.3

Reference Genes

ENSEMBL:ENSDARG00000099169

Other Identifiers

100003859

13234427

A_15_P393980

GO:0002376

GO:0003674

GO:0005153

GO:0005575

GO:0005576

GO:0006935

GO:0006950

GO:0006952

GO:0006955

GO:0008009

GO:0008150

GO:0030593

GO:0040011

GO:0042119

GO:0048870

Participates

as a member of

Homologues of CXCL6(38-114) [extracellular region] (Danio rerio)

Other forms of this molecule

cxcl8b.3 [extracellular region]

cxcl8b.3 [platelet alpha granule lumen]

cxcl8b.3 [tertiary granule lumen]

cxcl8b.3 [specific granule lumen]

cxcl8b.3 [extracellular region]

Inferred From

CXCL6(38-114) [extracellular region] (Homo sapiens)

Cross References

Ensembl

ENSDART00000167652, ENSDARP00000136707, ENSDARG00000099169

Cite Us!