Reactome | cxcr4a [plasma membrane]

cxcr4a [plasma membrane]

Stable Identifier

R-DRE-2980772

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

plasma membrane

Synonyms

CXCR4, Q7ZU02

Locations in the PathwayBrowser

Expand all

Signal Transduction (Danio rerio)

- Signaling by GPCR (Danio rerio)
  - GPCR downstream signalling (Danio rerio)
    - G alpha (i) signalling events (Danio rerio)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
        
        CXCR4,7:CXCL12 [plasma membrane] (Danio rerio)
        
        CXCR4,7 [plasma membrane] (Danio rerio)
        
        cxcr4a [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Danio rerio)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
        
        CXCR4,7:CXCL12 [plasma membrane] (Danio rerio)
        
        CXCR4,7 [plasma membrane] (Danio rerio)
        
        cxcr4a [plasma membrane] (Danio rerio)
  - GPCR ligand binding (Danio rerio)
    - Class A/1 (Rhodopsin-like receptors) (Danio rerio)
      - Peptide ligand-binding receptors (Danio rerio)
        
        Chemokine receptors bind chemokines (Danio rerio)
        
        Receptors CXCR4 and 7 bind CXCL12 ligand (Danio rerio)
        
        CXCR4,7 [plasma membrane] (Danio rerio)
        
        cxcr4a [plasma membrane] (Danio rerio)
        
        CXCR4,7:CXCL12 [plasma membrane] (Danio rerio)
        
        CXCR4,7 [plasma membrane] (Danio rerio)
        
        cxcr4a [plasma membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:Q7ZU02

Gene Names

cxcr4a

Reference Genes

BioGPS Gene:140747 cxcr4a

CTD Gene:140747 cxcr4a

ENSEMBL:ENSDARG00000057633

KEGG:dre:140747 cxcr4a

Monarch:140747 cxcr4a

NCBI Gene:140747 cxcr4a

UCSC:Q7ZU02 cxcr4a

Reference Transcript

RefSeq:NM_131882.3 cxcr4a

Participates

as a component of

CXCR4:CXCL12 [plasma membrane] (Danio rerio)

as a member of

CXCR4,7 [plasma membrane] (Danio rerio)

Inferred From

CXCR4 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_571957.2

ZFIN

ZDB-GENE-020102-1

Cite Us!