Reactome | mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane]

mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane]

Stable Identifier

R-DRE-2130667-5

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

lumenal side of endoplasmic reticulum membrane

Synonyms

HLA class II histocompatibility antigen, DP alpha chain precursor, Q95HJ4

Locations in the PathwayBrowser

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Immune System (Danio rerio)

- Adaptive Immune System (Danio rerio)
  - MHC class II antigen presentation (Danio rerio)
    - Dissociation of CANX from nonameric complex (Danio rerio)
      - 2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        HLA II alpha chain [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        alpha beta dimer:Ii trimer [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        HLA II alpha chain [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
      - 2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer:calnexin [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        HLA II alpha chain [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        alpha beta dimer:Ii trimer:calnexin [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        HLA II alpha chain [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
    - Formation of COPII vesicle (Danio rerio)
      - Nonameric complex [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        HLA II alpha chain [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
    - Formation of MHC II alpha beta heterodimer (Danio rerio)
      - HLA II alpha chain [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
      - MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        HLA II alpha chain [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
    - Formation of nonameric complex (Danio rerio)
      - 2xMHC II alpha beta heterodimer:alpha beta dimer:Ii trimer:calnexin [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        HLA II alpha chain [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        alpha beta dimer:Ii trimer:calnexin [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        HLA II alpha chain [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
      - MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        HLA II alpha chain [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
      - alpha beta dimer:Ii trimer:calnexin [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        HLA II alpha chain [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
    - Interaction of invariant chain trimer and MHC II alpha beta dimer (Danio rerio)
      - MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        HLA II alpha chain [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
      - alpha beta dimer:Ii trimer:calnexin [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        MHC II alpha beta heterodimer [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        HLA II alpha chain [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (Danio rerio)
        
        mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:Q95HJ4

Gene Names

mhc2d8.45b1

Reference Genes

BioGPS Gene:368846 mhc2d8.45b1

ENSEMBL:ENSDARG00000041705

Monarch:368846 mhc2d8.45b1

NCBI Gene:368846 mhc2d8.45b1

UCSC:Q95HJ4 mhc2d8.45b1

Reference Transcript

RefSeq:NM_001001595.1 mhc2d8.45b1

Other Identifiers

13248126

368846

A_15_P121494

A_15_P210761

A_15_P212836

A_15_P220446

CUST_25373_PI428451953

CUST_8036_PI428451958

CUST_9485_PI428451958

DRER14630

ENSDART00000046999_x_1

ENSDART00000046999_x_2

ENSDART00000061125

ENSDART00000075336

ENSDART00000098508

GO:0002376

GO:0002503

GO:0005765

GO:0006955

GO:0016020

GO:0019882

GO:0019886

GO:0023026

GO:0031902

GO:0042605

GO:0042613

GO:0050778

GO:0050870

GO:0065003

GT_Xhyb_NM_001001595.1_98041

GT_Xhyb_NM_001007035.1_107252

GT_Xhyb_NM_001077753.1_390455

GT_Xhyb_XM_005167256.1_205955

LOLS01447

MADDr01001939

MADDr01008001

NM_001001595

NM_001077753

Participates

as a member of

Homologues of HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (Danio rerio)

Other forms of this molecule

mhc2d8.45b1 [lysosomal membrane]

mhc2d8.45b1 [lumenal side of endoplasmic reticulum membrane]

mhc2d8.45b1 [ER to Golgi transport vesicle membrane]

mhc2d8.45b1 [Golgi membrane]

mhc2d8.45b1 [trans-Golgi network membrane]

mhc2d8.45b1 [transport vesicle membrane]

mhc2d8.45b1 [clathrin-coated endocytic vesicle membrane]

mhc2d8.45b1 [endocytic vesicle membrane]

mhc2d8.45b1 [lysosomal membrane]

mhc2d8.45b1 [plasma membrane]

Inferred From

HLA class II histocompatibility antigen, DP alpha chain precursor [lumenal side of endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_001001595.1

ENSEMBL

ENSDART00000158784, ENSDARP00000133249

ZFIN

ZDB-GENE-030616-396

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