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ActrIIB [plasma membrane]
Stable Identifier
R-DRE-201656
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
plasma membrane
Synonyms
ACVR2B, Q9YGU4
Locations in the PathwayBrowser
Expand all
Signal Transduction (Danio rerio)
Signaling by TGFB family members (Danio rerio)
Signaling by Activin (Danio rerio)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Danio rerio)
Activin A,AB,B:ACVR2A,B:ACVR1B [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
Activin A,AB,B:ACVR2A,B:p-ACVR1B [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Danio rerio)
Activin:ACVR2A,B:p-ACVR1B,C [plasma membrane] (Danio rerio)
Activin A,AB,B:ACVR2A,B:p-ACVR1B [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
Activin AB,B:ACVR2A,B:p-ACVR1C [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
Signaling by BMP (Danio rerio)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Danio rerio)
BMP:p-BMPR:Endofin:SMAD1/5/8 [early endosome membrane] (Danio rerio)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
An anchoring protein, Endofin, recruits R-Smad1/5/8 (Danio rerio)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
BMP:p-BMPR:Endofin:SMAD1/5/8 [early endosome membrane] (Danio rerio)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
BMP2 binds to the receptor complex (Danio rerio)
BMP:BMPRII:BMPRI [plasma membrane] (Danio rerio)
BMPRII:BMPRI [plasma membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
BMPRII:BMPRI [plasma membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
Formation of a heteromeric BMP receptor complex (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
BMPRII:BMPRI [plasma membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
I-Smad binds to type I receptor, preventing Smad1/5/8 from being activated (Danio rerio)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
BMP:p-BMPR:I-SMAD:SMURF [plasma membrane] (Danio rerio)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
I-Smad competes with R-Smad1/5/8 for type I receptor (Danio rerio)
BMP2:BMP type II receptor:Phospho-BMP type I receptor:I-SMAD [plasma membrane] (Danio rerio)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
Phospho-R-Smad1/5/8 dissociates from the receptor complex (Danio rerio)
BMP:p-BMPR:Endofin [early endosome membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
BMP:p-BMPR:Endofin:p-2S-SMAD1/5/8 [early endosome membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
Type II receptor phosphorylates type I receptor (Danio rerio)
BMP:BMPRII:BMPRI [plasma membrane] (Danio rerio)
BMPRII:BMPRI [plasma membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
BMP:BMPRII:p-4S-BMPRI [plasma membrane] (Danio rerio)
BMPRII dimer [plasma membrane] (Danio rerio)
Type II receptor [plasma membrane] (Danio rerio)
ActrIIB [plasma membrane] (Danio rerio)
External Reference Information
External Reference
UniProt:Q9YGU4
Gene Names
ActrIIB
Reference Genes
BioGPS Gene:30457 ActrIIB
CTD Gene:30457 ActrIIB
ENSEMBL:ENSDARG00000044422
KEGG Gene (Danio rerio):30457 ActrIIB
Monarch:30457 ActrIIB
NCBI Gene:30457 ActrIIB
Reference Transcript
RefSeq:NM_131210.3 ActrIIB
Participates
as a member of
Type II receptor [plasma membrane] (Danio rerio)
as a component of
Activin A,AB,B:ACVR2A,B:ACVR1B [plasma membrane] (Danio rerio)
Activin AB,B:ACVR2A,B:p-ACVR1C [plasma membrane] (Danio rerio)
Activin A,AB,B:ACVR2A,B:p-ACVR1B [plasma membrane] (Danio rerio)
Inferred From
ACVR2A,B [plasma membrane]
(Homo sapiens)
ACVR2B [plasma membrane]
(Homo sapiens)
Cross References
RefSeq
NP_571285.1
ZFIN
ZDB-GENE-980526-549
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