Reactome | fk84a07 [cytosol]

fk84a07 [cytosol]

Stable Identifier

R-DRE-200809

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

cytosol

Synonyms

ARPC2, Q6P2T5

Locations in the PathwayBrowser

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Developmental Biology (Danio rerio)

- Nervous system development (Danio rerio)
  - Axon guidance (Danio rerio)
    - EPH-Ephrin signaling (Danio rerio)
      - EPHB-mediated forward signaling (Danio rerio)
        
        N-WASP binds ARP2/3 and G-actin (Danio rerio)
        
        ARP2/3 complex (ATP bound) [cytosol] (Danio rerio)
        
        fk84a07 [cytosol] (Danio rerio)
        
        p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Danio rerio)
        
        ARP2/3 complex (ATP bound) [cytosol] (Danio rerio)
        
        fk84a07 [cytosol] (Danio rerio)

Signal Transduction (Danio rerio)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
  - Signaling by Rho GTPases (Danio rerio)
    - RHO GTPase Effectors (Danio rerio)
      - RHO GTPases Activate WASPs and WAVEs (Danio rerio)
        
        (WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Danio rerio)
        
        Mother filament:branching complex [cytosol] (Danio rerio)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Danio rerio)
        
        ARP2/3 complex (ATP bound) [cytosol] (Danio rerio)
        
        fk84a07 [cytosol] (Danio rerio)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Danio rerio)
        
        ARP2/3 complex (ATP bound) [cytosol] (Danio rerio)
        
        fk84a07 [cytosol] (Danio rerio)
        
        Branching and elongation of mother and daughter filaments (Danio rerio)
        
        Mother filament:ARP2/3:actin:ADP [cytosol] (Danio rerio)
        
        ARP2/3 complex (ATP bound) [cytosol] (Danio rerio)
        
        fk84a07 [cytosol] (Danio rerio)
        
        Mother filament:branching complex:daughter filament [cytosol] (Danio rerio)
        
        ARP2/3 complex (ATP bound) [cytosol] (Danio rerio)
        
        fk84a07 [cytosol] (Danio rerio)
        
        Detachment of WASP/WAVE (Danio rerio)
        
        Mother filament:ARP2/3:actin:ADP [cytosol] (Danio rerio)
        
        ARP2/3 complex (ATP bound) [cytosol] (Danio rerio)
        
        fk84a07 [cytosol] (Danio rerio)
        
        Mother filament:branching complex [cytosol] (Danio rerio)
        
        WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Danio rerio)
        
        ARP2/3 complex (ATP bound) [cytosol] (Danio rerio)
        
        fk84a07 [cytosol] (Danio rerio)

External Reference Information

External Reference

UniProt:Q6P2T5

Gene Names

fk84a07

Reference Genes

BioGPS Gene:327068 fk84a07

ENSEMBL:ENSDARG00000075989

ENSEMBL:ENSDARG00000075989.4 fk84a07

KEGG Gene (Danio rerio):327068 fk84a07

Monarch:327068 fk84a07

NCBI Gene:327068 fk84a07

Reference Transcript

RefSeq:NM_212699.1 fk84a07

Other Identifiers

13269831

327068

A_15_P109247

A_15_P208676

A_15_P346630

A_15_P473235

A_15_P741121

CJ012575

CUST_12719_PI428451958

DRER15163

DRER47239

ENSDART00000021726

ENSDART00000021726_1

ENSDART00000021726_2

ENSDART00000099803

GO:0003779

GO:0005198

GO:0005200

GO:0005737

GO:0005856

GO:0005885

GO:0007010

GO:0008092

GO:0015629

GO:0030041

GO:0030833

GO:0034314

GO:0042995

GO:0043226

GO:0051015

GO:0065003

GT_Spec_NM_212699.1_293125

LOLS11825

NM_212699

Participates

as a component of

ARP2/3 complex (ATP bound) [cytosol] (Danio rerio)

Inferred From

ARPC2 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_997864.1

ZFIN

ZDB-GENE-030131-5276

Ensembl

ENSDART00000099803, ENSDARP00000090576, ENSDARG00000075989

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