Reactome | mhc2b [plasma membrane]

mhc2b [plasma membrane]

Stable Identifier

R-DRE-197648-5

Type

Protein [EntityWithAccessionedSequence]

Species

Danio rerio

Compartment

plasma membrane

Synonyms

HLA class II histocompatibility antigen, DP, A0A2R8Q639

Locations in the PathwayBrowser

Expand all

Immune System (Danio rerio)

- Adaptive Immune System (Danio rerio)
  - MHC class II antigen presentation (Danio rerio)
    - Insertion of MHC II:Ii complex in to the plasma membrane (Danio rerio)
      - MHC class II alpha/beta/Ii nonamer [plasma membrane] (Danio rerio)
        
        MHC class II alpha/beta dimer [plasma membrane] (Danio rerio)
        
        HLA II beta chain [plasma membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP [plasma membrane] (Danio rerio)
        
        mhc2b [plasma membrane] (Danio rerio)
    - Internalization of MHC II:Ii clathrin coated vesicle (Danio rerio)
      - Clathrin coated MHC class II alpha/beta/Ii nonamer [plasma membrane] (Danio rerio)
        
        MHC class II alpha/beta/Ii nonamer [plasma membrane] (Danio rerio)
        
        MHC class II alpha/beta dimer [plasma membrane] (Danio rerio)
        
        HLA II beta chain [plasma membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP [plasma membrane] (Danio rerio)
        
        mhc2b [plasma membrane] (Danio rerio)
    - LAG3 (CD233) binds MHC II (Danio rerio)
      - LAG3:MHC II [plasma membrane] (Danio rerio)
        
        MHC class II alpha/beta dimer [plasma membrane] (Danio rerio)
        
        HLA II beta chain [plasma membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP [plasma membrane] (Danio rerio)
        
        mhc2b [plasma membrane] (Danio rerio)
      - MHC class II alpha/beta dimer [plasma membrane] (Danio rerio)
        
        HLA II beta chain [plasma membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP [plasma membrane] (Danio rerio)
        
        mhc2b [plasma membrane] (Danio rerio)
    - Recruitment of clathrin coated vesicle by Ii (Danio rerio)
      - Clathrin coated MHC class II alpha/beta/Ii nonamer [plasma membrane] (Danio rerio)
        
        MHC class II alpha/beta/Ii nonamer [plasma membrane] (Danio rerio)
        
        MHC class II alpha/beta dimer [plasma membrane] (Danio rerio)
        
        HLA II beta chain [plasma membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP [plasma membrane] (Danio rerio)
        
        mhc2b [plasma membrane] (Danio rerio)
      - MHC class II alpha/beta/Ii nonamer [plasma membrane] (Danio rerio)
        
        MHC class II alpha/beta dimer [plasma membrane] (Danio rerio)
        
        HLA II beta chain [plasma membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP [plasma membrane] (Danio rerio)
        
        mhc2b [plasma membrane] (Danio rerio)
    - Transport of antigen loaded MHC II molecules to surface (Danio rerio)
      - peptide loaded MHC class II [plasma membrane] (Danio rerio)
        
        MHC class II alpha/beta dimer [plasma membrane] (Danio rerio)
        
        HLA II beta chain [plasma membrane] (Danio rerio)
        
        Homologues of HLA class II histocompatibility antigen, DP [plasma membrane] (Danio rerio)
        
        mhc2b [plasma membrane] (Danio rerio)

External Reference Information

External Reference

UniProt:A0A2R8Q639

Gene Names

mhc2b

Reference Genes

ENSEMBL:ENSDARG00000104635

Other Identifiers

13247373

368615

A_15_P579987

A_15_P765811

CUST_23391_PI428451953

CUST_2592_PI428451958

DRER10933

ENSDART00000077802

ENSDART00000077802_1

ENSDART00000077802_2

GO:0002376

GO:0005575

GO:0005886

GO:0006955

GO:0008150

GO:0016020

GO:0016021

GO:0019882

GO:0032991

GO:0042613

GT_Spec_NM_001007206.2_390795

LOLS00816

MADDr01004964

NM_001007206

OTTDART00000001473

OTTDART00000001780

Participant Of

hasMember

Homologues of HLA class II histocompatibility antigen, DP [plasma membrane]

Other forms of this molecule

mhc2b [lysosomal membrane]

mhc2b [transport vesicle membrane]

mhc2b [clathrin-coated endocytic vesicle membrane]

mhc2b [endocytic vesicle membrane]

mhc2b [integral component of lumenal side of endoplasmic reticulum membrane]

mhc2b [ER to Golgi transport vesicle membrane]

mhc2b [Golgi membrane]

mhc2b [trans-Golgi network membrane]

mhc2b [lysosomal membrane]

mhc2b [plasma membrane]

Inferred From

HLA class II histocompatibility antigen, DP [plasma membrane] (Homo sapiens)

Cross References

Ensembl

ENSDARP00000148566, ENSDARG00000104635, ENSDART00000191281