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zgc:91975 [cytosol]
Stable Identifier
R-DRE-143379
Type
Protein [EntityWithAccessionedSequence]
Species
Danio rerio
Compartment
cytosol
Synonyms
GSPT2, Q68EH0
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Danio rerio)
Nonsense-Mediated Decay (NMD) (Danio rerio)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Danio rerio)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Danio rerio)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
eRF3:GDP [cytosol] (Danio rerio)
eRF3 [cytosol] (Danio rerio)
Homologues of GSPT2 [cytosol] (Danio rerio)
zgc:91975 [cytosol] (Danio rerio)
SMG1:UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
eRF3:GDP [cytosol] (Danio rerio)
eRF3 [cytosol] (Danio rerio)
Homologues of GSPT2 [cytosol] (Danio rerio)
zgc:91975 [cytosol] (Danio rerio)
SMG6 hydrolyzes mRNA with premature termination codon (Danio rerio)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Danio rerio)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
eRF3:GDP [cytosol] (Danio rerio)
eRF3 [cytosol] (Danio rerio)
Homologues of GSPT2 [cytosol] (Danio rerio)
zgc:91975 [cytosol] (Danio rerio)
p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Danio rerio)
Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Danio rerio)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
eRF3:GDP [cytosol] (Danio rerio)
eRF3 [cytosol] (Danio rerio)
Homologues of GSPT2 [cytosol] (Danio rerio)
zgc:91975 [cytosol] (Danio rerio)
SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Danio rerio)
Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Danio rerio)
eRF3:GDP [cytosol] (Danio rerio)
eRF3 [cytosol] (Danio rerio)
Homologues of GSPT2 [cytosol] (Danio rerio)
zgc:91975 [cytosol] (Danio rerio)
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Danio rerio)
Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Danio rerio)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Danio rerio)
eRF3:GDP [cytosol] (Danio rerio)
eRF3 [cytosol] (Danio rerio)
Homologues of GSPT2 [cytosol] (Danio rerio)
zgc:91975 [cytosol] (Danio rerio)
UPF1:eRF3 Complex on Translated mRNA [cytosol] (Danio rerio)
Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Danio rerio)
eRF3:GDP [cytosol] (Danio rerio)
eRF3 [cytosol] (Danio rerio)
Homologues of GSPT2 [cytosol] (Danio rerio)
zgc:91975 [cytosol] (Danio rerio)
Metabolism of proteins (Danio rerio)
Translation (Danio rerio)
Eukaryotic Translation Termination (Danio rerio)
N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer (Danio rerio)
ETF1 dimer:eRF3:GTP [cytosol] (Danio rerio)
eRF3:GTP [cytosol] (Danio rerio)
eRF3 [cytosol] (Danio rerio)
Homologues of GSPT2 [cytosol] (Danio rerio)
zgc:91975 [cytosol] (Danio rerio)
Me-Q185-ETF1 dimer:eRF3:GTP [cytosol] (Danio rerio)
eRF3:GTP [cytosol] (Danio rerio)
eRF3 [cytosol] (Danio rerio)
Homologues of GSPT2 [cytosol] (Danio rerio)
zgc:91975 [cytosol] (Danio rerio)
External Reference Information
External Reference
UniProt:Q68EH0
Gene Names
zgc:91975
Reference Genes
BioGPS Gene:445485 zgc:91975
ENSEMBL:ENSDARG00000031048
ENSEMBL:ENSDARG00000031048.7 zgc:91975
ENSEMBL:ENSDARG00000109388.1 zgc:91975
KEGG Gene (Danio rerio):445485 zgc:91975
Monarch:445485 zgc:91975
NCBI Gene:445485 zgc:91975
Reference Transcript
RefSeq:NM_001003992.1 zgc:91975
Other Identifiers
12984953
445485
A_15_P166611
BC080263.1
DRER05026
Dr.13814.1.S1_at
Dr.17154.1.A1_at
ENSDART00000041711
ENSDART00000041711_1
ENSDART00000041711_2
GO:0000166
GO:0003747
GO:0003824
GO:0003924
GO:0005525
GO:0006412
GO:0006415
GO:0016787
GO:0018444
GO:0045182
LOLS09304
LOLS12919
MADDr01009792
OTTDART00000027849
XM_694003
XM_694018
Participates
as a member of
Homologues of GSPT2 [cytosol] (Danio rerio)
Inferred From
GSPT2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001003992.1
ZFIN
ZDB-GENE-040822-36
Ensembl
ENSDARP00000041710
,
ENSDARG00000109388
,
ENSDART00000041711
,
ENSDART00000186853
,
ENSDARP00000157415
,
ENSDARG00000031048
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