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Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane]
Stable Identifier
R-DRE-1112594
Type
Complex
Species
Danio rerio
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Danio rerio)
Cytokine Signaling in Immune system (Danio rerio)
Signaling by Interleukins (Danio rerio)
Interleukin-6 family signaling (Danio rerio)
Interleukin-6 signaling (Danio rerio)
IL6ST is tyrosine phosphorylated (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
PTPN11 binds CBL (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11:CBL [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
PTPN11 is phosphorylated (Danio rerio)
IL6:Tyrosine phosphorylated hexameric IL-6 receptor:Activated JAKs:p-Y546,Y584-PTPN11 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
Phosphorylated STATs are released (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
SOCS3 binds IL6ST (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:SOCS3 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
Serine phosphorylation of STATs (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine/serine phosphorylated STAT1/3 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:SOCS3 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
Signal Transduction (Danio rerio)
MAPK family signaling cascades (Danio rerio)
MAPK1/MAPK3 signaling (Danio rerio)
RAF-independent MAPK1/3 activation (Danio rerio)
MAPK1 (ERK2) activation (Danio rerio)
MAP2K2 binds MAPK1 (Danio rerio)
IL6:Tyrosine phosphorylated hexameric IL-6 receptor:Activated JAKs:p-Y546,Y584-PTPN11 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
MAPK3 (ERK1) activation (Danio rerio)
MAP2K1 binds MAPK3 (Danio rerio)
IL6:Tyrosine phosphorylated hexameric IL-6 receptor:Activated JAKs:p-Y546,Y584-PTPN11 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane] (Danio rerio)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
IL6:IL6RA:Tyrosine phosphorylated IL6RB:Activated JAKs [plasma membrane]
(Danio rerio)
Participates
as an input of
SOCS3 binds IL6ST (Danio rerio)
Tyrosine phosphorylated IL6ST binds STAT1,STAT3 (Danio rerio)
as a component of
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine/serine phosphorylated STAT1/3 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:PTPN11 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:SOCS3 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:Tyrosine phosphorylated STAT1,STAT3 [plasma membrane] (Danio rerio)
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs:STAT1,STAT3 [plasma membrane] (Danio rerio)
IL6:Tyrosine phosphorylated hexameric IL-6 receptor:Activated JAKs:p-Y546,Y584-PTPN11 [plasma membrane] (Danio rerio)
as an output of
Phosphorylated STATs are released (Danio rerio)
IL6ST is tyrosine phosphorylated (Danio rerio)
Inferred From
Tyrosine phosphorylated IL6 receptor hexamer:Activated JAKs [plasma membrane]
(Homo sapiens)
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