Reactome | APEX1:SSB(AP->5'-dRP)-dsDNA [nucleoplasm]

APEX1:SSB(AP->5'-dRP)-dsDNA [nucleoplasm]

Stable Identifier

R-DRE-110334

Type

Complex

Species

Danio rerio

Compartment

nucleoplasm

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

APEX1 [nucleoplasm] (Danio rerio)
Ghost homologue of SSB(AP->5'-dRP)-dsDNA [nucleoplasm] (Danio rerio)

Participates

as an input of

Recruitment of POLB to the AP site (Danio rerio)
Oxidative damage to the AP site (Danio rerio)

as a component of

POLB:APEX1:SSB(AP->5'-dRP)-dsDNA [nucleoplasm] (Danio rerio)

as an output of

APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Danio rerio)

Inferred From

APEX1:SSB(AP->5'-dRP)-dsDNA [nucleoplasm] (Homo sapiens)

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