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KDM1A [nucleoplasm]
Stable Identifier
R-DME-996769
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
Q9VW97
Locations in the PathwayBrowser
Expand all
Chromatin organization (Drosophila melanogaster)
Chromatin modifying enzymes (Drosophila melanogaster)
HDACs deacetylate histones (Drosophila melanogaster)
HDAC1:2-containing complex binds HDAC2 Inhibitors (Drosophila melanogaster)
HDAC1:2-containing complex [nucleoplasm] (Drosophila melanogaster)
BHC complex [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
CoREST complex [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
HDAC1:2-containing complex:HDAC2 inhibitors [nucleoplasm] (Drosophila melanogaster)
HDAC1:2-containing complex [nucleoplasm] (Drosophila melanogaster)
BHC complex [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
CoREST complex [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
HDAC1:2-containing complex deacetylate histones (Drosophila melanogaster)
HDAC1:2-containing complex [nucleoplasm] (Drosophila melanogaster)
BHC complex [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
CoREST complex [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
HDAC1:2-containing complex:HDAC2 inhibitors [nucleoplasm] (Drosophila melanogaster)
HDAC1:2-containing complex [nucleoplasm] (Drosophila melanogaster)
BHC complex [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
CoREST complex [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
Hemostasis (Drosophila melanogaster)
Factors involved in megakaryocyte development and platelet production (Drosophila melanogaster)
REST recruits the BHC complex (Drosophila melanogaster)
BHC complex [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
BHC complex:REST:REST DNA binding sites [nucleoplasm] (Drosophila melanogaster)
BHC complex [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Estrogen-dependent gene expression (Drosophila melanogaster)
KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
KDM1A is recruited to MYC and BCL2 genes (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases activate PKNs (Drosophila melanogaster)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Drosophila melanogaster)
Demethylase KDM1A binds KLK2 and KLK3 promoters (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Drosophila melanogaster)
KDM1A [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q9VW97
Reference Genes
BioGPS Gene:40217
CTD Gene:40217
ENSEMBL:FBgn0260397
Flybase:FBgn0260397
KEGG Gene (Drosophila melanogaster):Dmel_CG17149
Monarch:40217
NCBI Gene:40217
Reference Transcript
RefSeq:NM_168835.2
RefSeq:NM_140937.3
Other Identifiers
155096_at
1634524_s_at
40217
GO:0000122
GO:0003682
GO:0003824
GO:0005515
GO:0005634
GO:0005694
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0007474
GO:0016491
GO:0017053
GO:0022414
GO:0030154
GO:0032453
GO:0033696
GO:0034720
GO:0036211
GO:0043226
GO:0045944
GO:0048477
GO:0048856
GO:0050660
GO:0070828
GO:0090309
GO:0140096
GO:0140682
Participates
as an output of
KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Drosophila melanogaster)
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Drosophila melanogaster)
as an input of
KDM1A is recruited to MYC and BCL2 genes (Drosophila melanogaster)
Demethylase KDM1A binds KLK2 and KLK3 promoters (Drosophila melanogaster)
as a component of
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Drosophila melanogaster)
BHC complex [nucleoplasm] (Drosophila melanogaster)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Drosophila melanogaster)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Drosophila melanogaster)
CoREST complex [nucleoplasm] (Drosophila melanogaster)
Inferred From
KDM1A [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_649194.1
,
NP_730497.1
Flybase
FBgn0260397
PRO
Q9VW97
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