Ncd is a dimer

Stable Identifier
R-DME-990504
Type
Reaction [binding]
Species
Drosophila melanogaster
Compartment
cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Ncd is a dimer
Ncd is a minus-end-directed kinesin. Cooperative interactions between the motor heads in the active dimer influence the interactions of each respective motor domain with the microtubule. These interactions are required for ATP-dependent dissociation; one function of the partner motor domain may be to weaken the interaction of the adjacent head with the microtubule (Mackey & Gilbert 2000).
Literature References
PubMed ID Title Journal Year
10574799 The crystal structure of the minus-end-directed microtubule motor protein ncd reveals variable dimer conformations

Cohen-Addad, C, Kozielski, F, Burmeister, WP, Wade, RH, De Bonis, S

Structure 1999
Participants
Input
Output
Orthologous Events
Kinesin-14 is a dimer (Homo sapiens)
Authored
Akkerman, JW  (2010-10-29)
Reviewed
Ouwehand, WH  (2010-11-12)
Created
Jupe, S  (2010-11-03)
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