Reactome | Ligand-bound PPARG:RXRA:NCoR/SMRT:PDK4 gene:nucleosomes [nucleoplasm]

Ligand-bound PPARG:RXRA:NCoR/SMRT:PDK4 gene:nucleosomes [nucleoplasm]

Stable Identifier

R-DME-9864608

Type

Complex

Species

Drosophila melanogaster

Compartment

nucleoplasm

Locations in the PathwayBrowser

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Gene expression (Transcription) (Drosophila melanogaster)

- Epigenetic regulation of gene expression (Drosophila melanogaster)
  - Epigenetic regulation by WDR5-containing histone modifying complexes (Drosophila melanogaster)
    - Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Drosophila melanogaster)
      - Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Drosophila melanogaster)
        
        MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Drosophila melanogaster)
        
        RXRA binds ligands (Drosophila melanogaster)
        
        PPARG ligands:PPARG:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Drosophila melanogaster)
        
        Ligand-bound PPARG:RXRA:NCoR/SMRT:PDK4 gene:nucleosomes [nucleoplasm] (Drosophila melanogaster)

General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

Participates

as a member of

PPARG ligands:PPARG:RXRA:Corepressors:adipogenesis genes:Nucleosomes [nucleoplasm] (Drosophila melanogaster)

Inferred From

Ligand-bound PPARG:RXRA:NCoR/SMRT:PDK4 gene:nucleosomes [nucleoplasm] (Homo sapiens)

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