Reactome | Vha100-3 [lysosomal membrane]

Vha100-3 [lysosomal membrane]

Stable Identifier

R-DME-9640188

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

lysosomal membrane

Synonyms

TCIRG1, A1ZBF7

Locations in the PathwayBrowser

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Cellular responses to external stimuli (Drosophila melanogaster)

- Cellular responses to stress (Drosophila melanogaster)
  - Amino acids regulate mTORC1 (Drosophila melanogaster)
    - RRAGA,B exchanges GDP for GTP (Drosophila melanogaster)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase [lysosomal membrane] (Drosophila melanogaster)
        
        ATP6V0 [lysosomal membrane] (Drosophila melanogaster)
        
        Homologues of TCIRG1 [lysosomal membrane] (Drosophila melanogaster)
        
        Vha100-3 [lysosomal membrane] (Drosophila melanogaster)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase [lysosomal membrane] (Drosophila melanogaster)
        
        ATP6V0 [lysosomal membrane] (Drosophila melanogaster)
        
        Homologues of TCIRG1 [lysosomal membrane] (Drosophila melanogaster)
        
        Vha100-3 [lysosomal membrane] (Drosophila melanogaster)
    - RRAGA,B hydrolyzes GTP (Drosophila melanogaster)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase [lysosomal membrane] (Drosophila melanogaster)
        
        ATP6V0 [lysosomal membrane] (Drosophila melanogaster)
        
        Homologues of TCIRG1 [lysosomal membrane] (Drosophila melanogaster)
        
        Vha100-3 [lysosomal membrane] (Drosophila melanogaster)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase [lysosomal membrane] (Drosophila melanogaster)
        
        ATP6V0 [lysosomal membrane] (Drosophila melanogaster)
        
        Homologues of TCIRG1 [lysosomal membrane] (Drosophila melanogaster)
        
        Vha100-3 [lysosomal membrane] (Drosophila melanogaster)
    - RRAGC,D exchanges GTP for GDP (Drosophila melanogaster)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase [lysosomal membrane] (Drosophila melanogaster)
        
        ATP6V0 [lysosomal membrane] (Drosophila melanogaster)
        
        Homologues of TCIRG1 [lysosomal membrane] (Drosophila melanogaster)
        
        Vha100-3 [lysosomal membrane] (Drosophila melanogaster)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase [lysosomal membrane] (Drosophila melanogaster)
        
        ATP6V0 [lysosomal membrane] (Drosophila melanogaster)
        
        Homologues of TCIRG1 [lysosomal membrane] (Drosophila melanogaster)
        
        Vha100-3 [lysosomal membrane] (Drosophila melanogaster)
    - RRAGC,D hydrolyzes GTP (Drosophila melanogaster)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase [lysosomal membrane] (Drosophila melanogaster)
        
        ATP6V0 [lysosomal membrane] (Drosophila melanogaster)
        
        Homologues of TCIRG1 [lysosomal membrane] (Drosophila melanogaster)
        
        Vha100-3 [lysosomal membrane] (Drosophila melanogaster)
      - v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase [lysosomal membrane] (Drosophila melanogaster)
        
        ATP6V0 [lysosomal membrane] (Drosophila melanogaster)
        
        Homologues of TCIRG1 [lysosomal membrane] (Drosophila melanogaster)
        
        Vha100-3 [lysosomal membrane] (Drosophila melanogaster)
    - mTORC1 binds RHEB:GTP (Drosophila melanogaster)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase [lysosomal membrane] (Drosophila melanogaster)
        
        ATP6V0 [lysosomal membrane] (Drosophila melanogaster)
        
        Homologues of TCIRG1 [lysosomal membrane] (Drosophila melanogaster)
        
        Vha100-3 [lysosomal membrane] (Drosophila melanogaster)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase [lysosomal membrane] (Drosophila melanogaster)
        
        ATP6V0 [lysosomal membrane] (Drosophila melanogaster)
        
        Homologues of TCIRG1 [lysosomal membrane] (Drosophila melanogaster)
        
        Vha100-3 [lysosomal membrane] (Drosophila melanogaster)
    - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Drosophila melanogaster)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase [lysosomal membrane] (Drosophila melanogaster)
        
        ATP6V0 [lysosomal membrane] (Drosophila melanogaster)
        
        Homologues of TCIRG1 [lysosomal membrane] (Drosophila melanogaster)
        
        Vha100-3 [lysosomal membrane] (Drosophila melanogaster)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase:Ragulator [lysosomal membrane] (Drosophila melanogaster)
        
        v-ATPase [lysosomal membrane] (Drosophila melanogaster)
        
        ATP6V0 [lysosomal membrane] (Drosophila melanogaster)
        
        Homologues of TCIRG1 [lysosomal membrane] (Drosophila melanogaster)
        
        Vha100-3 [lysosomal membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:A1ZBF7

Gene Names

Vha100-3

Reference Genes

BioGPS Gene:246543 Vha100-3

CTD Gene:246543 Vha100-3

ENSEMBL:FBgn0028669

Flybase:FBgn0028669

KEGG Gene (Drosophila melanogaster):Dmel_CG30329 Vha100-3

Monarch:246543 Vha100-3

NCBI Gene:246543 Vha100-3

UCSC:A1ZBF7 Vha100-3

Reference Transcript

RefSeq:NM_166313.2 Vha100-3

Other Identifiers

1627133_at

246543

GO:0000220

GO:0003674

GO:0005575

GO:0005622

GO:0005737

GO:0005773

GO:0005886

GO:0006810

GO:0006811

GO:0007035

GO:0008150

GO:0015078

GO:0015991

GO:0016020

GO:0016021

GO:0016471

GO:0016787

GO:0019899

GO:0022857

GO:0032991

GO:0033179

GO:0042592

GO:0043226

GO:0046961

GO:0051117

GO:0055085

GO:1902600

Participant Of

hasMember

Homologues of TCIRG1 [lysosomal membrane]

Other forms of this molecule

Vha100-3 [plasma membrane]

Vha100-3 [ficolin-1-rich granule membrane]

Vha100-3 [phagocytic vesicle membrane]

Vha100-3 [endosome membrane]

Inferred From

TCIRG1 [lysosomal membrane] (Homo sapiens)

Cross References

RefSeq

NP_725837.1

Flybase

FBgn0028669

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