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Pex5 [peroxisomal membrane]
Stable Identifier
R-DME-9033489
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
peroxisomal membrane
Synonyms
PEX5 isoform L, O46085
Locations in the PathwayBrowser
Expand all
Autophagy (Drosophila melanogaster)
Macroautophagy (Drosophila melanogaster)
Selective autophagy (Drosophila melanogaster)
Pexophagy (Drosophila melanogaster)
ATM dimer:PEX5 phosphorylates PEX5 (Drosophila melanogaster)
ATM dimer:PEX5 [peroxisomal membrane] (Drosophila melanogaster)
ATM:PEX5 [peroxisomal membrane] (Drosophila melanogaster)
Pex5 [peroxisomal membrane] (Drosophila melanogaster)
ATM:PEX5 binds ATM (Drosophila melanogaster)
ATM dimer:PEX5 [peroxisomal membrane] (Drosophila melanogaster)
ATM:PEX5 [peroxisomal membrane] (Drosophila melanogaster)
Pex5 [peroxisomal membrane] (Drosophila melanogaster)
ATM:PEX5 [peroxisomal membrane] (Drosophila melanogaster)
Pex5 [peroxisomal membrane] (Drosophila melanogaster)
ATM:PEX5 translocates from cytosol to peroxisomal membrane (Drosophila melanogaster)
ATM:PEX5 [peroxisomal membrane] (Drosophila melanogaster)
Pex5 [peroxisomal membrane] (Drosophila melanogaster)
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Protein ubiquitination (Drosophila melanogaster)
E3 ubiquitin ligases ubiquitinate target proteins (Drosophila melanogaster)
PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Drosophila melanogaster)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Drosophila melanogaster)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Drosophila melanogaster)
Pex5 [peroxisomal membrane] (Drosophila melanogaster)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Drosophila melanogaster)
Pex5 [peroxisomal membrane] (Drosophila melanogaster)
PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Drosophila melanogaster)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Drosophila melanogaster)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Drosophila melanogaster)
Pex5 [peroxisomal membrane] (Drosophila melanogaster)
Protein localization (Drosophila melanogaster)
Peroxisomal protein import (Drosophila melanogaster)
Cargo of PEX5L:PEX7 translocates from the cytosol to the peroxisomal matrix (Drosophila melanogaster)
PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Drosophila melanogaster)
Pex5 [peroxisomal membrane] (Drosophila melanogaster)
Cargo of PEX5S,L translocates from the cytosol to the peroxisomal matrix (Drosophila melanogaster)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Drosophila melanogaster)
Pex5 [peroxisomal membrane] (Drosophila melanogaster)
PEX2:PEX10:PEX12 binds PEX5L (in PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12) and Ub:UBE2D1,2,3 (Drosophila melanogaster)
PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane] (Drosophila melanogaster)
PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Drosophila melanogaster)
Pex5 [peroxisomal membrane] (Drosophila melanogaster)
PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Drosophila melanogaster)
Pex5 [peroxisomal membrane] (Drosophila melanogaster)
PEX2:PEX10:PEX12 binds PEX5S,L (in PEX5S:PEX13:PEX14) and Ub:UBE2D1,2,3 (Drosophila melanogaster)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Drosophila melanogaster)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Drosophila melanogaster)
Pex5 [peroxisomal membrane] (Drosophila melanogaster)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Drosophila melanogaster)
Pex5 [peroxisomal membrane] (Drosophila melanogaster)
PEX2:PEX10:PEX12 monoubiquitinates PEX5L at cysteine-11 (Drosophila melanogaster)
PEX2:PEX10:PEX12:PEX5L:Ub:UBE2D1,2,3:PEX7:PEX13:PEX14 [peroxisomal membrane] (Drosophila melanogaster)
PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Drosophila melanogaster)
Pex5 [peroxisomal membrane] (Drosophila melanogaster)
PEX2:PEX10:PEX12 monoubiquitinates PEX5S,L at cysteine-11 (Drosophila melanogaster)
PEX2:PEX10:PEX12:PEX5S,L:Ub:UBE2D1,2,3:PEX13:PEX14 [peroxisomal membrane] (Drosophila melanogaster)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Drosophila melanogaster)
Pex5 [peroxisomal membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:O46085
Gene Names
Pex5
Reference Genes
BioGPS Gene:31141 Pex5
ENSEMBL:FBgn0023516
FlyBase:FBgn0023516
Monarch:31141 Pex5
NCBI Gene:31141 Pex5
UCSC:O46085 Pex5
Reference Transcript
RefSeq:NM_166910.2 Pex5
Other Identifiers
143993_at
1633962_a_at
31141
GO:0005052
GO:0005515
GO:0005777
GO:0005778
GO:0005829
GO:0006886
GO:0007031
GO:0016020
GO:0016558
GO:0016560
GO:0043226
GO:0055085
GO:0072347
Participates
as a component of
PEX5L:PEX7:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Drosophila melanogaster)
PEX5S,L:PEX13:PEX14:PEX2:PEX10:PEX12 [peroxisomal membrane] (Drosophila melanogaster)
ATM:PEX5 [peroxisomal membrane] (Drosophila melanogaster)
Other forms of this molecule
Pex5 [cytosol]
Pex5 [peroxisomal membrane]
phospho-Pex5 [peroxisomal membrane]
phospho-Pex5 [peroxisomal membrane]
Pex5 [cytosol]
Inferred From
PEX5S,L [peroxisomal membrane]
(Homo sapiens)
PEX5 isoform S [peroxisomal membrane]
(Homo sapiens)
PEX5 isoform L [peroxisomal membrane]
(Homo sapiens)
PEX5 [peroxisomal membrane]
(Homo sapiens)
Cross References
RefSeq
NP_726771.1
ENSEMBL
FBtr0070367
,
FBpp0070351
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9VPB8
2
Pex14 [cytosol]
(R-DME-9603806)
Pex14 [peroxisomal membrane]
(R-DME-9033101)
0.547
2
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