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Cul4 [nucleoplasm]
Stable Identifier
R-DME-8952514
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
G76-NEDD8-K705-CUL4A, Q5BI50
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Neddylation (Drosophila melanogaster)
AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex (Drosophila melanogaster)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Drosophila melanogaster)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Drosophila melanogaster)
Cul4 [nucleoplasm] (Drosophila melanogaster)
COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex (Drosophila melanogaster)
NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] (Drosophila melanogaster)
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Drosophila melanogaster)
Cul4 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q5BI50
Gene Names
Cul4
Reference Genes
BioGPS Gene:35780 Cul4
ENSEMBL:FBgn0033260
FlyBase:FBgn0033260
KEGG:dme:Dmel_CG8711 Cul4
Monarch:35780 Cul4
NCBI Gene:35780 Cul4
UCSC:Q5BI50 Cul4
Reference Transcript
RefSeq:NM_001169613.1 Cul4
RefSeq:NM_136508.4 Cul4
Other Identifiers
153360_at
1624041_at
35780
GO:0000209
GO:0005634
GO:0006511
GO:0006974
GO:0007307
GO:0008407
GO:0016567
GO:0022414
GO:0030163
GO:0030674
GO:0031146
GO:0031461
GO:0031625
GO:0035332
GO:0043161
GO:0043226
GO:0045732
GO:0045879
GO:0060090
GO:0080008
GO:0160072
Participates
as a component of
NEDD8-CRL4 E3 ligase complex [nucleoplasm] (Drosophila melanogaster)
Other forms of this molecule
Cul4 [nucleoplasm]
Cul4 [nucleoplasm]
Cul4 [nucleoplasm]
Inferred From
NEDD8:CUL4 [nucleoplasm]
(Homo sapiens)
G76-NEDD8-K705-CUL4A [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
neddylated lysine (monoNEDD8 [nucleoplasm]) at 705 (in Homo sapiens)
Coordinate
705
Modification
monoNEDD8 [nucleoplasm]
PsiMod Name
neddylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a nedd8 protein.
Cross References
RefSeq
NP_610352.2
,
NP_001163084.1
ENSEMBL
FBtr0088821
,
FBpp0290569
,
FBpp0087897
,
FBtr0301355
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