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EMRE [mitochondrial inner membrane]
Stable Identifier
R-DME-8949227
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
mitochondrial inner membrane
Synonyms
SMDT1, Q7JX57
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Drosophila melanogaster)
Mitochondrial protein degradation (Drosophila melanogaster)
AFG3L2:SPG7 binds SMDT1 (EMRE) (Drosophila melanogaster)
AFG3L2:SPG7:SMDT1 [mitochondrial inner membrane] (Drosophila melanogaster)
EMRE [mitochondrial inner membrane] (Drosophila melanogaster)
EMRE [mitochondrial inner membrane] (Drosophila melanogaster)
AFG3L2:SPG7 degrades SMDT1 (EMRE) (Drosophila melanogaster)
AFG3L2:SPG7:SMDT1 [mitochondrial inner membrane] (Drosophila melanogaster)
EMRE [mitochondrial inner membrane] (Drosophila melanogaster)
Transport of small molecules (Drosophila melanogaster)
Mitochondrial calcium ion transport (Drosophila melanogaster)
MCU translocates calcium from the mitochondrial intermembrane space to the mitochondrial matrix (Drosophila melanogaster)
MCU complex [mitochondrial inner membrane] (Drosophila melanogaster)
EMRE [mitochondrial inner membrane] (Drosophila melanogaster)
Processing of SMDT1 (Drosophila melanogaster)
AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU (Drosophila melanogaster)
EMRE [mitochondrial inner membrane] (Drosophila melanogaster)
PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) (Drosophila melanogaster)
EMRE [mitochondrial inner membrane] (Drosophila melanogaster)
SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex (Drosophila melanogaster)
EMRE [mitochondrial inner membrane] (Drosophila melanogaster)
MCU complex [mitochondrial inner membrane] (Drosophila melanogaster)
EMRE [mitochondrial inner membrane] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7JX57
Gene Names
EMRE
Reference Genes
BioGPS Gene:37071 EMRE
ENSEMBL:FBgn0062440
Flybase:FBgn0062440
KEGG Gene (Drosophila melanogaster):Dmel_CG17680 EMRE
Monarch:37071 EMRE
NCBI Gene:37071 EMRE
UCSC:Q7JX57 EMRE
Reference Transcript
RefSeq:NM_137450.2 EMRE
Other Identifiers
142776_at
1624683_at
37071
GO:0002376
GO:0003674
GO:0005575
GO:0005739
GO:0005743
GO:0006811
GO:0006816
GO:0006851
GO:0016020
GO:0036444
GO:0043226
GO:0045089
GO:0050829
GO:0051560
GO:0055065
GO:0055085
GO:0098542
GO:1990246
Participates
as an input of
AFG3L2:SPG7 binds SMDT1 (EMRE) (Drosophila melanogaster)
SMDT1 assists in assembling MCU, MCUB, MICU1, MICU2 (or MICU3) yielding the MCU complex (Drosophila melanogaster)
AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU (Drosophila melanogaster)
as a component of
AFG3L2:SPG7:SMDT1 [mitochondrial inner membrane] (Drosophila melanogaster)
MCU complex [mitochondrial inner membrane] (Drosophila melanogaster)
as an output of
PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) (Drosophila melanogaster)
Other forms of this molecule
EMRE [mitochondrial matrix]
EMRE [mitochondrial inner membrane]
Inferred From
SMDT1 [mitochondrial inner membrane]
(Homo sapiens)
Cross References
RefSeq
NP_611294.1
Flybase
FBgn0062440
PRO
Q7JX57
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