Reactome | Gpa2 [extracellular region]

Gpa2 [extracellular region]

Stable Identifier

R-DME-8942422

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

extracellular region

Synonyms

GPHA2, A0A6I8WFJ4

Locations in the PathwayBrowser

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Signal Transduction (Drosophila melanogaster)

- Signaling by GPCR (Drosophila melanogaster)
  - GPCR downstream signalling (Drosophila melanogaster)
    - G alpha (s) signalling events (Drosophila melanogaster)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Drosophila melanogaster)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Drosophila melanogaster)
        
        TSHR:Thyrotropin [plasma membrane] (Drosophila melanogaster)
        
        Thyrostimulin [extracellular region] (Drosophila melanogaster)
        
        Gpa2 [extracellular region] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Drosophila melanogaster)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Drosophila melanogaster)
        
        TSHR:Thyrotropin [plasma membrane] (Drosophila melanogaster)
        
        Thyrostimulin [extracellular region] (Drosophila melanogaster)
        
        Gpa2 [extracellular region] (Drosophila melanogaster)
  - GPCR ligand binding (Drosophila melanogaster)
    - Class A/1 (Rhodopsin-like receptors) (Drosophila melanogaster)
      - Hormone ligand-binding receptors (Drosophila melanogaster)
        
        Thyroid-stimulating hormone receptor can bind TSH, Thyrostimulin (Drosophila melanogaster)
        
        TSHR:Thyrotropin [plasma membrane] (Drosophila melanogaster)
        
        Thyrostimulin [extracellular region] (Drosophila melanogaster)
        
        Gpa2 [extracellular region] (Drosophila melanogaster)
        
        Thyrostimulin [extracellular region] (Drosophila melanogaster)
        
        Gpa2 [extracellular region] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:A0A6I8WFJ4

Gene Names

Gpa2

Reference Genes

BioGPS Gene:5740142 Gpa2

ENSEMBL:FBgn0261386

Flybase:FBgn0261386

KEGG Gene (Drosophila melanogaster):Dmel_CG17878 Gpa2

Monarch:5740142 Gpa2

NCBI Gene:5740142 Gpa2

Reference Transcript

RefSeq:NM_001110584.2 Gpa2

Other Identifiers

5740142

GO:0001664

GO:0005179

GO:0005576

GO:0005615

GO:0007166

GO:0007186

GO:0023052

GO:0046982

GO:0048018

GO:0051427

GO:0098772

Participates

as a component of

Thyrostimulin [extracellular region] (Drosophila melanogaster)

Inferred From

GPHA2 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_001104054.2

Flybase

FBgn0261386

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