Reactome | Skp2 [cytosol]

Skp2 [cytosol]

Stable Identifier

R-DME-8854063

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

cytosol

Synonyms

FBXL18, Q7YZ95

Locations in the PathwayBrowser

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Cell Cycle (Drosophila melanogaster)

- Cell Cycle, Mitotic (Drosophila melanogaster)
  - Mitotic G2-G2/M phases (Drosophila melanogaster)
    - G2/M Transition (Drosophila melanogaster)
      - FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Drosophila melanogaster)
        
        SCF-FBXL18 ubiquitinates FBXL7 (Drosophila melanogaster)
        
        SKP1:CUL1:RBX1:FBXL18 [cytosol] (Drosophila melanogaster)
        
        Skp2 [cytosol] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q7YZ95

Gene Names

Skp2

Reference Genes

BioGPS Gene:40548 Skp2

ENSEMBL:FBgn0037236

FlyBase:FBgn0037236

KEGG Gene (Drosophila melanogaster):Dmel_CG9772 Skp2

Monarch:40548 Skp2

NCBI Gene:40548 Skp2

UCSC:Q7YZ95 Skp2

Reference Transcript

Other Identifiers

153298_at

1637091_a_at

40548

GO:0000278

GO:0003824

GO:0005515

GO:0007113

GO:0016301

GO:0016310

GO:0016740

GO:0019005

GO:0030163

GO:0031146

GO:0031647

GO:0035220

GO:0045787

GO:0048749

GO:0048856

Participates

as a component of

SKP1:CUL1:RBX1:FBXL18 [cytosol] (Drosophila melanogaster)

Other forms of this molecule

Skp2 [nucleoplasm]

Skp2 [cytosol]

Skp2 [nucleoplasm]

Inferred From

FBXL18 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_730815.2, NP_730816.3

Flybase

FBgn0037236

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O77430 skpA	3	SKPA [cytosol] (R-DME-205785) SkpA [nucleoplasm] (R-DME-187538) SkpA [cytosol] (R-DME-174150)	0.553	2
UniProt:Q9VHN1 Q9VHN1			0.553	3

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