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EIF2S3 [cytosol]
Stable Identifier
R-DME-72514
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
Q24208
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to mitochondrial stress (Drosophila melanogaster)
DELE1(143-515):EIF2AK1 enhances phosphorylation of EIF2S1 (EIF2alpha) (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
p-S52-EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
Unfolded Protein Response (UPR) (Drosophila melanogaster)
PERK regulates gene expression (Drosophila melanogaster)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
p-S52-EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
Metabolism of proteins (Drosophila melanogaster)
Translation (Drosophila melanogaster)
Eukaryotic Translation Initiation (Drosophila melanogaster)
Cap-dependent Translation Initiation (Drosophila melanogaster)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Drosophila melanogaster)
Translation initiation complex formation (Drosophila melanogaster)
Formation of translation initiation complexes containing mRNA that does not circularize (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
48S complex [cytosol] (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
Formation of the ternary complex, and subsequently, the 43S complex (Drosophila melanogaster)
De novo formation of eIF2:GTP (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
Formation of the 43S pre-initiation complex (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
Met-tRNAi binds to eIF2:GTP to form the ternary complex (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
Recycling of eIF2:GDP (Drosophila melanogaster)
Formation of eIF2:GDP:eIF2B intermediate (Drosophila melanogaster)
eIF2:GDP [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
eIF2:GDP: eIF2B [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
eIF2 activation (Drosophila melanogaster)
eIF2:GDP: eIF2B [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
Ribosomal scanning and start codon recognition (Drosophila melanogaster)
Ribosomal scanning (Drosophila melanogaster)
48S complex [cytosol] (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
Start codon recognition (Drosophila melanogaster)
48S complex [cytosol] (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
L13a-mediated translational silencing of Ceruloplasmin expression (Drosophila melanogaster)
Association of phospho-L13a with GAIT element of Ceruloplasmin mRNA (Drosophila melanogaster)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
phospho-L13a associated wth the 3' UTR GAIT element of ceruloplasmin mRNA within the translation initiation complex [cytosol] (Drosophila melanogaster)
43S: Ceruloplasmin mRNA:eIF4F:eIF4B:eIF4H:PABP [cytosol] (Drosophila melanogaster)
43S complex [cytosol] (Drosophila melanogaster)
ternary complex [cytosol] (Drosophila melanogaster)
eIF2:GTP [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
Transport of small molecules (Drosophila melanogaster)
ABC-family proteins mediated transport (Drosophila melanogaster)
ABCF1 binds EIF2 (Drosophila melanogaster)
ABCF1:EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S3 [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q24208
Reference Genes
BioGPS Gene:41843
ENSEMBL:FBgn0263740
Flybase:FBgn0263740
KEGG Gene (Drosophila melanogaster):Dmel_CG43665
Monarch:41843
NCBI Gene:41843
Reference Transcript
RefSeq:NM_169629.2
RefSeq:NM_169630.2
RefSeq:NM_001275658.1
Other Identifiers
153645_at
1632577_a_at
41843
GO:0000049
GO:0000166
GO:0001731
GO:0002181
GO:0003723
GO:0003743
GO:0003824
GO:0003924
GO:0005525
GO:0005850
GO:0006412
GO:0006413
GO:0016282
GO:0016787
GO:0043614
GO:0045182
GO:0045903
GO:0065003
Participates
as a component of
p-S52-EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
EIF2S1:EIF2S2:EIF2S3 [cytosol] (Drosophila melanogaster)
Inferred From
EIF2S3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001262587.1
,
NP_731993.1
,
NP_731994.1
Flybase
FBgn0263740
PRO
Q24208
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