Reactome | GLS [mitochondrial matrix]

GLS [mitochondrial matrix]

Stable Identifier

R-DME-70610

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

mitochondrial matrix

Synonyms

GLS2, Q1RL13

Locations in the PathwayBrowser

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Gene expression (Transcription) (Drosophila melanogaster)

- RNA Polymerase II Transcription (Drosophila melanogaster)
  - Generic Transcription Pathway (Drosophila melanogaster)
    - Transcriptional Regulation by TP53 (Drosophila melanogaster)
      - TP53 Regulates Metabolic Genes (Drosophila melanogaster)
        
        glutamine + H2O => glutamate + NH4+ [GLS] (Drosophila melanogaster)
        
        GLS dimers [mitochondrial matrix] (Drosophila melanogaster)
        
        GLS2 dimer [mitochondrial matrix] (Drosophila melanogaster)
        
        GLS [mitochondrial matrix] (Drosophila melanogaster)

Neuronal System (Drosophila melanogaster)

- Transmission across Chemical Synapses (Drosophila melanogaster)
  - Neurotransmitter release cycle (Drosophila melanogaster)
    - Glutamate Neurotransmitter Release Cycle (Drosophila melanogaster)
      - glutamine + H2O => glutamate + NH4+ [GLS] (Drosophila melanogaster)
        
        GLS dimers [mitochondrial matrix] (Drosophila melanogaster)
        
        GLS2 dimer [mitochondrial matrix] (Drosophila melanogaster)
        
        GLS [mitochondrial matrix] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q1RL13

Gene Names

GLS

Reference Genes

BioGPS Gene:36396 GLS

ENSEMBL:FBgn0261625

Flybase:FBgn0261625

KEGG Gene (Drosophila melanogaster):Dmel_CG42708 GLS

Monarch:36396 GLS

NCBI Gene:36396 GLS

Reference Transcript

RefSeq:NM_001169658.2 GLS

Other Identifiers

1634658_a_at

36396

GO:0003824

GO:0004359

GO:0005515

GO:0005739

GO:0006520

GO:0006537

GO:0006541

GO:0006543

GO:0016787

GO:0043226

Participates

as a component of

GLS2 dimer [mitochondrial matrix] (Drosophila melanogaster)

Other forms of this molecule

GLS [mitochondrial matrix]

Inferred From

GLS2 [mitochondrial matrix] (Homo sapiens)

Cross References

RefSeq

NP_001163129.1

Flybase

FBgn0261625

OpenTargets

ENSG00000115419

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