Reactome | Dmel\CG15160 [nucleoplasm]

Dmel\CG15160 [nucleoplasm]

Stable Identifier

R-DME-6814906

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

nucleoplasm

Synonyms

RPRD2, X2JAA3

Locations in the PathwayBrowser

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Gene expression (Transcription) (Drosophila melanogaster)

- RNA Polymerase II Transcription (Drosophila melanogaster)
  - RNA polymerase II transcribes snRNA genes (Drosophila melanogaster)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Dmel\CG15160 [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Dmel\CG15160 [nucleoplasm] (Drosophila melanogaster)
    - Integrator complex processes the 3' end of snRNA (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Dmel\CG15160 [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Dmel\CG15160 [nucleoplasm] (Drosophila melanogaster)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Dmel\CG15160 [nucleoplasm] (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Dmel\CG15160 [nucleoplasm] (Drosophila melanogaster)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Drosophila melanogaster)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Drosophila melanogaster)
        
        Dmel\CG15160 [nucleoplasm] (Drosophila melanogaster)
      - RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Drosophila melanogaster)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RPRD1A,B:RPRD2:RPAP2 [nucleoplasm] (Drosophila melanogaster)
        
        Dmel\CG15160 [nucleoplasm] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:X2JAA3

Gene Names

Dmel\CG15160

Reference Genes

BioGPS Gene:35109 Dmel\CG15160

ENSEMBL:FBgn0032688

Flybase:FBgn0032688

Monarch:35109 Dmel\CG15160

NCBI Gene:35109 Dmel\CG15160

Reference Transcript

RefSeq:NM_001299118.1 Dmel\CG15160

Other Identifiers

146440_at

35109

GO:0000785

GO:0000993

GO:0003674

GO:0005634

GO:0005654

GO:0005694

GO:0016071

GO:0016591

GO:0031124

GO:0043226

Participates

as a component of

Inferred From

RPRD2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001286047.1

Flybase

FBgn0032688