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Pten [nucleoplasm]
Stable Identifier
R-DME-6807264
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
MonoUb-K13,K289-PTEN, Q7KMQ6
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
PTEN Regulation (Drosophila melanogaster)
Regulation of PTEN localization (Drosophila melanogaster)
Monoubiquitinated PTEN translocates to the nucleus (Drosophila melanogaster)
Pten [nucleoplasm] (Drosophila melanogaster)
USP7 deubiquitinates monoubiquitinated PTEN (Drosophila melanogaster)
Pten [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:Q7KMQ6 Pten
Gene Names
Pten, CG5671, Dmel_CG5671
Reference Genes
BioGPS Gene:43991 Pten
KEGG:dme:Dmel_CG5671 Pten
Monarch:43991 Pten
NCBI Gene:43991 Pten
UCSC:Q7KMQ6 Pten
Reference Transcript
RefSeq:NM_058075.4 Pten
RefSeq:NM_058074.4 Pten
RefSeq:NM_134322.3 Pten
RefSeq:NM_001169462.2 Pten
Other Identifiers
144125_at
1628114_s_at
1630738_s_at
43991
GO:0002164
GO:0002376
GO:0003824
GO:0004438
GO:0004721
GO:0004722
GO:0004725
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006469
GO:0006470
GO:0006629
GO:0006914
GO:0007010
GO:0007032
GO:0007425
GO:0007552
GO:0008104
GO:0008138
GO:0008285
GO:0008360
GO:0008361
GO:0009887
GO:0009888
GO:0010008
GO:0010506
GO:0010888
GO:0014065
GO:0014067
GO:0016239
GO:0016311
GO:0016314
GO:0016787
GO:0016791
GO:0017018
GO:0022414
GO:0030036
GO:0030165
GO:0030198
GO:0030308
GO:0030336
GO:0030707
GO:0031104
GO:0031647
GO:0035011
GO:0035069
GO:0035204
GO:0035206
GO:0035212
GO:0040014
GO:0040015
GO:0042052
GO:0042059
GO:0042594
GO:0042690
GO:0042995
GO:0043065
GO:0043226
GO:0043491
GO:0045571
GO:0045614
GO:0045792
GO:0046621
GO:0046627
GO:0046855
GO:0046856
GO:0048167
GO:0048542
GO:0048681
GO:0048856
GO:0048870
GO:0050773
GO:0051717
GO:0051726
GO:0051800
GO:0051895
GO:0051896
GO:0051898
GO:0052866
GO:0055088
GO:0071711
GO:0090175
GO:0098542
GO:0140096
GO:1901888
Participates
as an input of
USP7 deubiquitinates monoubiquitinated PTEN (Drosophila melanogaster)
as an output of
Monoubiquitinated PTEN translocates to the nucleus (Drosophila melanogaster)
Other forms of this molecule
Pten [cytosol]
Pten [nucleoplasm]
Pten [cytosol]
Pten [cytosol]
Pten [cytosol]
phospho-Pten [cytosol]
phospho-Pten [cytosol]
phospho-Pten [cytosol]
phospho-Pten [cytosol]
Pten [nucleoplasm]
Pten [cytosol]
DPTEN [cytosol]
Inferred From
MonoUb-K13,K289-PTEN [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (ubiquitin [nucleoplasm]) at 13 (in Homo sapiens)
Coordinate
13
Modification
Ub [nucleoplasm]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Name
ubiquitinylated lysine (ubiquitin [nucleoplasm]) at 289 (in Homo sapiens)
Coordinate
289
Modification
Ub [nucleoplasm]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_001162933.1
,
NP_477423.1
,
NP_477422.2
,
NP_599149.1
ENSEMBL
FBtr0301521
,
FBpp0088843
,
FBpp0289789
,
FBtr0300562
,
FBtr0089904
,
FBtr0089900
,
FBpp0088839
,
FBpp0290736
FlyBase
FBgn0026379
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