Reactome | Tsp [extracellular region]

Tsp [extracellular region]

Stable Identifier

R-DME-66518

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

extracellular region

Synonyms

THBS1, Q9VM97

Locations in the PathwayBrowser

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Hemostasis (Drosophila melanogaster)

- Platelet activation, signaling and aggregation (Drosophila melanogaster)
  - Response to elevated platelet cytosolic Ca2+ (Drosophila melanogaster)
    - Platelet degranulation (Drosophila melanogaster)
      - Exocytosis of platelet alpha granule contents (Drosophila melanogaster)
        
        Platelet alpha granule contents [extracellular region] (Drosophila melanogaster)
        
        THBS1 trimer [extracellular region] (Drosophila melanogaster)
        
        Tsp [extracellular region] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VM97

Gene Names

Tsp

Reference Genes

BioGPS Gene:33941 Tsp

ENSEMBL:FBgn0031850

Flybase:FBgn0031850

KEGG Gene (Drosophila melanogaster):Dmel_CG11326 Tsp

Monarch:33941 Tsp

NCBI Gene:33941 Tsp

UCSC:Q9VM97 Tsp

Reference Transcript

Other Identifiers

142426_at

1636251_at

33941

GO:0003674

GO:0005509

GO:0005575

GO:0005576

GO:0005927

GO:0007155

GO:0007517

GO:0008150

GO:0008201

GO:0016203

GO:0031012

GO:0032991

GO:0033627

GO:0043167

GO:0048856

GO:0062023

Participates

as a member of

Extracellular matrix ligands [extracellular region] (Drosophila melanogaster)

as a component of

as an input of

Interaction of integrin alphaIIb beta 3 with THBS1 (Thrombospondin-1) (Drosophila melanogaster)

Other forms of this molecule

Tsp [endoplasmic reticulum lumen]

Tsp [platelet alpha granule lumen]

Tsp [extracellular region]

Inferred From

Thrombospondin [extracellular region] (Homo sapiens)

THBS1 [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_523495.2, NP_001137802.1

Flybase

FBgn0031850

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9VE85	2	Nup43 [nuclear envelope] (R-DME-157739) Nup43 [cytosol] (R-DME-376243)	0.462	2
UniProt:P91659	3	Dmel\CG2187 [plasma membrane] (R-DME-5215942) Dmel\CG2187 [plasma membrane] (R-DME-209833) Dmel\CG2187 [plasma membrane] (R-DME-429769)	0.462	2