Reactome | cni [ER to Golgi transport vesicle membrane]

cni [ER to Golgi transport vesicle membrane]

Stable Identifier

R-DME-5689780

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

ER to Golgi transport vesicle membrane

Synonyms

CNIH2, P49858

Locations in the PathwayBrowser

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Metabolism of proteins (Drosophila melanogaster)

- Post-translational protein modification (Drosophila melanogaster)
  - Asparagine N-linked glycosylation (Drosophila melanogaster)
    - Transport to the Golgi and subsequent modification (Drosophila melanogaster)
      - ER to Golgi Anterograde Transport (Drosophila melanogaster)
        
        COPII-mediated vesicle transport (Drosophila melanogaster)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Drosophila melanogaster)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        CNIH2,3:GRIA1 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        cni [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII coat binds TRAPPCII and RAB1:GDP (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        CNIH2,3:GRIA1 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        cni [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        CNIH2,3:GRIA1 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        cni [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        Nucleotide exchange on RAB1 (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        CNIH2,3:GRIA1 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        cni [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        CNIH2,3:GRIA1 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        cni [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        CNIH2,3:GRIA1 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        cni [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        CNIH2,3:GRIA1 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        cni [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)

Vesicle-mediated transport (Drosophila melanogaster)

- Membrane Trafficking (Drosophila melanogaster)
  - ER to Golgi Anterograde Transport (Drosophila melanogaster)
    - COPII-mediated vesicle transport (Drosophila melanogaster)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Drosophila melanogaster)
        
        COPII cargo:receptors:v:SNAREs:GOLGA2:GORASP1:USO1 homodimer [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        CNIH2,3:GRIA1 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        cni [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
      - COPII coat binds TRAPPCII and RAB1:GDP (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        CNIH2,3:GRIA1 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        cni [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        CNIH2,3:GRIA1 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        cni [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
      - Nucleotide exchange on RAB1 (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GDP [COPII-coated ER to Golgi transport vesicle] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        CNIH2,3:GRIA1 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        cni [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        CNIH2,3:GRIA1 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        cni [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
      - RAB1:GTP binds USO1 and GORASP1:GOLGA2 (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        CNIH2,3:GRIA1 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        cni [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP:USO1 homodimer:GOLGA2:GORASP1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs:TRAPPCII:RAB1:GTP [COPII-coated ER to Golgi transport vesicle] (Drosophila melanogaster)
        
        COPII cargo:receptors:SEC23:SEC24:SEC13:SEC31:SEC23IP:v-SNAREs [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        COPII cargo:receptors [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        CNIH2,3:GRIA1 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)
        
        cni [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:P49858

Gene Names

cni

Reference Genes

BioGPS Gene:34967 cni

CTD Gene:34967 cni

ENSEMBL:FBgn0000339

Flybase:FBgn0000339

KEGG Gene (Drosophila melanogaster):Dmel_CG5855 cni

Monarch:34967 cni

NCBI Gene:34967 cni

UCSC:P49858 cni

Reference Transcript

Other Identifiers

143104_at

1633961_s_at

34967

GO:0000003

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005783

GO:0005789

GO:0006810

GO:0006888

GO:0007310

GO:0007350

GO:0008150

GO:0009790

GO:0009952

GO:0015031

GO:0016020

GO:0016021

GO:0016192

GO:0021700

GO:0022607

GO:0030134

GO:0030154

GO:0031410

GO:0043226

GO:0046843

GO:0048646

GO:0048856

Participates

as a component of

CNIH2,3:GRIA1 [ER to Golgi transport vesicle membrane] (Drosophila melanogaster)

Other forms of this molecule

cni [endoplasmic reticulum-Golgi intermediate compartment membrane]

cni [endoplasmic reticulum membrane]

Inferred From

CNIH2,3 [ER to Golgi transport vesicle membrane] (Homo sapiens)

CNIH2 [ER to Golgi transport vesicle membrane] (Homo sapiens)

CNIH3 [ER to Golgi transport vesicle membrane] (Homo sapiens)

Cross References

RefSeq

NP_001260495.1, NP_477068.1, NP_723959.1

Flybase

FBgn0000339

PRO

P49858

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:D2NUJ7 D2NUJ7			0.488	2
UniProt:Q7JRF1 Q7JRF1			0.488	2
UniProt:Q0E985 Q0E985			0.488	2
UniProt:Q9W4B6	3	BcDNA:RE01432 [specific granule membrane] (R-DME-6800916-4) BcDNA:RE01432 [plasma membrane] (R-DME-6806275-4) BcDNA:RE01432 [azurophil granule membrane] (R-DME-6799141-4)	0.488	2
UniProt:Q8SY72 SMCO4			0.488	2
UniProt:Q9VPD6 Q9VPD6			0.488	2
UniProt:Q7JW78 Q7JW78			0.488	2
UniProt:M9MSP0 M9MSP0			0.488	2
UniProt:Q9VNR8 Q9VNR8			0.488	2
UniProt:Q9VVX6	3	Bet1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-DME-5688142) Bet1 [transport vesicle] (R-DME-6808719) Bet1 [Golgi membrane] (R-DME-6807743)	0.488	2
UniProt:Q8INN3 Q8INN3			0.488	2
UniProt:Q9VRL2	4	Membrin [ER to Golgi transport vesicle membrane] (R-DME-5689800) Membrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-DME-535472) Membrin [endoplasmic reticulum membrane] (R-DME-5689451) Membrin [Golgi membrane] (R-DME-6807755)	0.488	2
UniProt:A1Z6Z3 A1Z6Z3			0.488	2
UniProt:Q9VIL1 Q9VIL1			0.488	2
UniProt:P22810 HMOC			0.488	2
UniProt:Q8IPG2 Q8IPG2			0.488	2
UniProt:Q8MS59	1	wat [peroxisomal membrane] (R-DME-390430)	0.488	2
UniProt:Q9VEJ4	1	Dmel\CG5823 [cytosol] (R-DME-947637)	0.488	2
UniProt:Q9VL16	4	phospho-Dmel\CG5676 [mitochondrial outer membrane] (R-DME-8948140) phospho-Dmel\CG5676 [mitochondrial outer membrane] (R-DME-8934915) Dmel\CG5676 [mitochondrial outer membrane] (R-DME-8934922) phospho-Dmel\CG5676 [mitochondrial outer membrane] (R-DME-8934910)	0.488	2

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