Reactome | Spn88Ea [endoplasmic reticulum-Golgi intermediate compartment membrane]

Spn88Ea [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-DME-5689734-18

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Synonyms

(Glc)3(GlcNAc)2(Man)9-SERPINA1, Q9VFC2

Locations in the PathwayBrowser

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Metabolism of proteins (Drosophila melanogaster)

- Post-translational protein modification (Drosophila melanogaster)
  - Asparagine N-linked glycosylation (Drosophila melanogaster)
    - Transport to the Golgi and subsequent modification (Drosophila melanogaster)
      - ER to Golgi Anterograde Transport (Drosophila melanogaster)
        
        COPII-mediated vesicle transport (Drosophila melanogaster)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Drosophila melanogaster)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        Spn88Ea [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)

Vesicle-mediated transport (Drosophila melanogaster)

- Membrane Trafficking (Drosophila melanogaster)
  - ER to Golgi Anterograde Transport (Drosophila melanogaster)
    - COPII-mediated vesicle transport (Drosophila melanogaster)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Drosophila melanogaster)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        Spn88Ea [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VFC2

Gene Names

Spn88Ea

Reference Genes

BioGPS Gene:49804 Spn88Ea

ENSEMBL:FBgn0028984

Flybase:FBgn0028984

KEGG Gene (Drosophila melanogaster):Dmel_CG18525 Spn88Ea

Monarch:49804 Spn88Ea

NCBI Gene:49804 Spn88Ea

UCSC:Q9VFC2 Spn88Ea

Reference Transcript

Other Identifiers

152581_at

1636943_s_at

49804

GO:0002376

GO:0003674

GO:0004867

GO:0005575

GO:0005576

GO:0005615

GO:0006950

GO:0007165

GO:0008150

GO:0009058

GO:0010466

GO:0010951

GO:0019748

GO:0030234

GO:0030414

GO:0040007

GO:0042438

GO:0045751

GO:0045824

GO:0045861

GO:0048526

GO:0048856

Participates

as a member of

Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)

Other forms of this molecule

Spn88Ea [extracellular region]

Spn88Ea [platelet alpha granule lumen]

Spn88Ea [extracellular region]

Spn88Ea [platelet dense granule lumen]

Spn88Ea [extracellular region]

Spn88Ea [plasma membrane]

Spn88Ea [extracellular region]

Spn88Ea [endoplasmic reticulum lumen]

Spn88Ea [extracellular region]

Spn88Ea [endoplasmic reticulum lumen]

Spn88Ea [COPII-coated ER to Golgi transport vesicle]

Spn88Ea [extracellular region]

Spn88Ea [ficolin-1-rich granule lumen]

Spn88Ea [azurophil granule lumen]

Spn88Ea [extracellular region]

Spn88Ea [secretory granule lumen]

Spn88Ea [extracellular region]

phospho-Spn88Ea [endoplasmic reticulum lumen]

Spn88Ea [endoplasmic reticulum lumen]

Inferred From

(Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Modified Residues

Name

N4-(N-acetylamino)glucosyl-L-asparagine (N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue (ChEBI:59084)) at unknown position

Modification

N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-yl group (ChEBI:59084)

PsiMod Name

N4-(N-acetylamino)glucosyl-L-asparagine

PsiMod Definition

A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.

Cross References

RefSeq

NP_788678.1, NP_524954.2

Flybase

FBgn0028984

PRO

Q9VFC2