Reactome | Spn88Eb [endoplasmic reticulum-Golgi intermediate compartment membrane]

Spn88Eb [endoplasmic reticulum-Golgi intermediate compartment membrane]

Stable Identifier

R-DME-5689734-18

Type

Protein [EntityWithAccessionedSequence]

Species

Drosophila melanogaster

Compartment

endoplasmic reticulum-Golgi intermediate compartment membrane

Synonyms

(Glc)3(GlcNAc)2(Man)9-SERPINA1, Q9VFC1

Locations in the PathwayBrowser

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Metabolism of proteins (Drosophila melanogaster)

- Post-translational protein modification (Drosophila melanogaster)
  - Asparagine N-linked glycosylation (Drosophila melanogaster)
    - Transport to the Golgi and subsequent modification (Drosophila melanogaster)
      - ER to Golgi Anterograde Transport (Drosophila melanogaster)
        
        COPII-mediated vesicle transport (Drosophila melanogaster)
        
        BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Drosophila melanogaster)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        Spn88Eb [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)

Vesicle-mediated transport (Drosophila melanogaster)

- Membrane Trafficking (Drosophila melanogaster)
  - ER to Golgi Anterograde Transport (Drosophila melanogaster)
    - COPII-mediated vesicle transport (Drosophila melanogaster)
      - BET1:GOSR2:STX5 bind v-SNARES on tethered vesicle (Drosophila melanogaster)
        
        COPII cargo:receptors [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        LMAN receptor:glycosylated cargo [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)
        
        Spn88Eb [endoplasmic reticulum-Golgi intermediate compartment membrane] (Drosophila melanogaster)

External Reference Information

External Reference

UniProt:Q9VFC1

Gene Names

Spn88Eb

Reference Genes

BioGPS Gene:41829 Spn88Eb

CTD Gene:41829 Spn88Eb

ENSEMBL:FBgn0038299

Flybase:FBgn0038299

KEGG Gene (Drosophila melanogaster):Dmel_CG6687 Spn88Eb

Monarch:41829 Spn88Eb

NCBI Gene:41829 Spn88Eb

UCSC:Q9VFC1 Spn88Eb

Reference Transcript

RefSeq:NM_142170.3 Spn88Eb

Other Identifiers

141353_at

1636946_at

41829

GO:0003674

GO:0004867

GO:0005575

GO:0005576

GO:0005615

GO:0006950

GO:0008150

GO:0009620

GO:0010466

GO:0010951

GO:0030234

GO:0030414

GO:0040007

GO:0045861

GO:0048856

GO:0051301

GO:1990399

GO:2000035

Participant Of

hasMember

Homologues of (Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum-Golgi intermediate compartment membrane]

Other forms of this molecule

Spn88Eb [cytosol]

Spn88Eb [extracellular region]

Spn88Eb [platelet alpha granule lumen]

Spn88Eb [extracellular region]

Spn88Eb [platelet dense granule lumen]

Spn88Eb [endoplasmic reticulum lumen]

Spn88Eb [extracellular region]

Spn88Eb [plasma membrane]

Spn88Eb [extracellular region]

Spn88Eb [endoplasmic reticulum lumen]

Spn88Eb [extracellular region]

Spn88Eb [endoplasmic reticulum lumen]

Spn88Eb [COPII-coated ER to Golgi transport vesicle]

Spn88Eb [lysosomal lumen]

Spn88Eb [extracellular region]

Spn88Eb [endoplasmic reticulum lumen]

phospho-Spn88Eb [endoplasmic reticulum lumen]

Spn88Eb [secretory granule lumen]

Spn88Eb [extracellular region]

Spn88Eb [ficolin-1-rich granule membrane]

Spn88Eb [plasma membrane]

Spn88Eb [tertiary granule membrane]

Spn88Eb [ficolin-1-rich granule lumen]

Spn88Eb [extracellular region]

Spn88Eb [secretory granule membrane]

Spn88Eb [azurophil granule lumen]

Spn88Eb [extracellular region]

Inferred From

(Glc)3(GlcNAc)2(Man)9-SERPINA1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (Homo sapiens)

Modified Residues

Name

N4-(N-acetylamino)glucosyl-L-asparagine (N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue (ChEBI:59084)) at unknown position

Modification

N-{alpha-Glc-(1->2)-alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->3)-(alpha-Man-(1->2)-alpha-Man-(1->6))-alpha-Man-(1->6))-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-yl group (ChEBI:59084)

PsiMod Name

N4-(N-acetylamino)glucosyl-L-asparagine

PsiMod Definition

A protein modification that effectively converts an L-asparagine residue to N4-(N-acetylaminoglucosyl)-L-asparagine.

Cross References

RefSeq

NP_650427.1

Flybase

FBgn0038299

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