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phospho-p-S,3T-CHEK2 [nucleoplasm]
Stable Identifier
R-DME-5683784
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
O61267
Locations in the PathwayBrowser
Expand all
Cell Cycle (Drosophila melanogaster)
Cell Cycle Checkpoints (Drosophila melanogaster)
G1/S DNA Damage Checkpoints (Drosophila melanogaster)
p53-Dependent G1/S DNA damage checkpoint (Drosophila melanogaster)
p53-Dependent G1 DNA Damage Response (Drosophila melanogaster)
Stabilization of p53 (Drosophila melanogaster)
CHEK2 phosphorylates TP53 (Drosophila melanogaster)
phospho-p-S,3T-CHEK2 [nucleoplasm] (Drosophila melanogaster)
p53-Independent G1/S DNA damage checkpoint (Drosophila melanogaster)
p53-Independent DNA Damage Response (Drosophila melanogaster)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A (Drosophila melanogaster)
Phosphorylation of Cdc25A at Ser-123 by Chk2 (Drosophila melanogaster)
phospho-p-S,3T-CHEK2 [nucleoplasm] (Drosophila melanogaster)
G2/M Checkpoints (Drosophila melanogaster)
G2/M DNA damage checkpoint (Drosophila melanogaster)
Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex (Drosophila melanogaster)
Phosphorylation of Cdc25C at Ser216 by CHEK2 (Drosophila melanogaster)
phospho-p-S,3T-CHEK2 [nucleoplasm] (Drosophila melanogaster)
p-T68-CHEK2 autophosphorylates (Drosophila melanogaster)
phospho-p-S,3T-CHEK2 [nucleoplasm] (Drosophila melanogaster)
DNA Repair (Drosophila melanogaster)
DNA Double-Strand Break Repair (Drosophila melanogaster)
DNA Double Strand Break Response (Drosophila melanogaster)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Drosophila melanogaster)
p-T68-CHEK2 autophosphorylates (Drosophila melanogaster)
phospho-p-S,3T-CHEK2 [nucleoplasm] (Drosophila melanogaster)
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
Regulation of TP53 Activity (Drosophila melanogaster)
Regulation of TP53 Activity through Phosphorylation (Drosophila melanogaster)
CHEK2 phosphorylates TP53 (Drosophila melanogaster)
phospho-p-S,3T-CHEK2 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:O61267
Reference Genes
BioGPS Gene:35288
CTD Gene:35288
ENSEMBL:FBgn0019686
FlyBase:FBgn0019686
KEGG:dme:Dmel_CG10895
Monarch:35288
NCBI Gene:35288
UCSC:O61267
Reference Transcript
RefSeq:NM_057870.4
RefSeq:NM_165318.3
RefSeq:NM_057871.4
Other Identifiers
154411_at
1625038_s_at
35288
GO:0000077
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0006282
GO:0006355
GO:0006468
GO:0006915
GO:0006919
GO:0006974
GO:0007281
GO:0008630
GO:0008656
GO:0012501
GO:0016607
GO:0016740
GO:0022414
GO:0030717
GO:0035234
GO:0043226
GO:0044773
GO:0045944
GO:0048856
GO:0050321
GO:0051091
GO:0071480
GO:0071481
GO:0072332
GO:0098772
GO:0106310
GO:0140096
Participates
as an output of
p-T68-CHEK2 autophosphorylates (Drosophila melanogaster)
Other forms of this molecule
phospho-p-T68-CHEK2 [nucleoplasm]
Inferred From
p-S,3T-CHEK2 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 68 (in Homo sapiens)
Coordinate
68
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 379 (in Homo sapiens)
Coordinate
379
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 383 (in Homo sapiens)
Coordinate
383
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 387 (in Homo sapiens)
Coordinate
387
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_724241.1
,
NP_477218.1
,
NP_477219.1
ENSEMBL
FBtr0081328
,
FBpp0080860
PRO
O61267
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