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Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane]
Stable Identifier
R-DME-5654203
Type
Complex
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
Negative regulation of the PI3K/AKT network (Drosophila melanogaster)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Drosophila melanogaster)
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activator:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activator:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by FGFR (Drosophila melanogaster)
Signaling by FGFR3 (Drosophila melanogaster)
Downstream signaling of activated FGFR3 (Drosophila melanogaster)
PI-3K cascade:FGFR3 (Drosophila melanogaster)
Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Activated FGFR3:p-FRS2 [plasma membrane]
(Drosophila melanogaster)
GRB2:GAB1:PIK3R1 [cytosol]
(Drosophila melanogaster)
Participates
as an output of
Activated FGFR3:p-FRS2 binds GRB2:GAB1:PIK3R1 (Drosophila melanogaster)
as a component of
Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Inferred From
Activated FGFR3:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane]
(Homo sapiens)
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