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Activated FGFR2:p-FRS2 [plasma membrane]
Stable Identifier
R-DME-5654201
Type
Complex
Species
Drosophila melanogaster
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
PIP3 activates AKT signaling (Drosophila melanogaster)
Negative regulation of the PI3K/AKT network (Drosophila melanogaster)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Drosophila melanogaster)
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activator:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activator:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF/MAP kinase cascade (Drosophila melanogaster)
RAS GEFs promote RAS nucleotide exchange (Drosophila melanogaster)
RAS GEFs [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS:GRB2:SOS1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by FGFR (Drosophila melanogaster)
Signaling by FGFR2 (Drosophila melanogaster)
Downstream signaling of activated FGFR2 (Drosophila melanogaster)
FRS-mediated FGFR2 signaling (Drosophila melanogaster)
Activated FGFR2 phosphorylates FRS2 (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2 phosphorylates PPTN11 (Drosophila melanogaster)
Activated FGFR2:p-FRS:PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:SOS1 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR2:p-FRS:GRB2:SOS1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS:p-PTPN11 activates RAS nucleotide exchange (Drosophila melanogaster)
Activated FGFR2:p-FRS:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:pFRS binds GRB2:SOS1 (Drosophila melanogaster)
Activated FGFR2:p-FRS [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS:GRB2:SOS1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
PI-3K cascade:FGFR2 (Drosophila melanogaster)
Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PPTN11 binds GRB2:GAB1:PI3KR1 (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Negative regulation of FGFR2 signaling (Drosophila melanogaster)
CBL ubiquitinates FRS2 and FGFR2 (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:p-CBL:GRB2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Ub-Activated FGFR2 complex:Ub-p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:p-CBL:GRB2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
p-CBL:GRB2 binds p-FRS2:activated FGFR2 (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11:p-CBL:GRB2 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2 [plasma membrane] (Drosophila melanogaster)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Activated FGFR2 [plasma membrane]
(Drosophila melanogaster)
phospho-Dmel\CG13398 [plasma membrane]
(Drosophila melanogaster)
Participates
as a member of
Activated FGFR2:p-FRS [plasma membrane] (Drosophila melanogaster)
as an input of
Activated FGFR2:p-FRS2 binds GRB2:GAB1:PIK3R1 (Drosophila melanogaster)
as an output of
Activated FGFR2 phosphorylates FRS2 (Drosophila melanogaster)
as a component of
Activated FGFR2:p-FRS2:GRB2:GAB1:PIK3R1 [plasma membrane] (Drosophila melanogaster)
Activated FGFR2:p-FRS2:p-PTPN11 [plasma membrane] (Drosophila melanogaster)
Inferred From
Activated FGFR2:p-FRS2 [plasma membrane]
(Homo sapiens)
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