Phosphorylated PER rebinds to phosphorylated TIM

Stable Identifier
R-DME-538900
Type
Reaction [binding]
Species
Drosophila melanogaster
Compartment
ReviewStatus
5/5
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Once in the nucleus, phosphorylated Timeless (TIM) and Period (PER) reform their heterodimer.
Literature References
PubMed ID Title Journal Year
8600384 A light-entrainment mechanism for the Drosophila circadian clock

Myers, MP, Qian, Z, Rosbash, M, Zeng, H

Nature 1996
8596938 Resetting the Drosophila clock by photic regulation of PER and a PER-TIM complex

Bae, K, Itsukaichi, T, Edery, I, Lee, C, Parikh, V

Science 1996
11430804 Phosphorylation of period is influenced by cycling physical associations of double-time, period, and timeless in the Drosophila clock

Saez, L, Young, MW, Rothenfluh, A, Kloss, B

Neuron 2001
16410523 PER-TIM interactions in living Drosophila cells: an interval timer for the circadian clock

Saez, L, Young, MW, Meyer, P

Science 2006
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