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Rrp1 [nucleoplasm]
Stable Identifier
R-DME-50119
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
nucleoplasm
Synonyms
APEX1, P27864
Locations in the PathwayBrowser
Expand all
DNA Repair (Drosophila melanogaster)
Base Excision Repair (Drosophila melanogaster)
Resolution of Abasic Sites (AP sites) (Drosophila melanogaster)
APEX1 mediates endonucleolytic cleavage at the 5' side of the AP site (Drosophila melanogaster)
APEX1:AP-dsDNA [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
APEX1:SSB(AP->5'-dRP)-dsDNA [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
Displacement of DNA glycosylase by APEX1 (Drosophila melanogaster)
Displacement of NTHL1 glycosylase by APEX1 at the AP site (Drosophila melanogaster)
APEX1:AP-dsDNA [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
Displacement of OGG1 glycosylase by APEX1 at the AP site (Drosophila melanogaster)
APEX1:AP-dsDNA [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
Displacement of SMUG1 glycosylase by APEX1 at the AP site (Drosophila melanogaster)
APEX1:AP-dsDNA [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
Displacement of TDG glycosylase by APEX1 at the AP site (Drosophila melanogaster)
APEX1:AP-dsDNA [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Drosophila melanogaster)
Oxidative damage to the AP site (Drosophila melanogaster)
APEX1:SSB(5'-ddRP)-dsDNA [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
APEX1:SSB(AP->5'-dRP)-dsDNA [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
PCNA-Dependent Long Patch Base Excision Repair (Drosophila melanogaster)
LIG1 binds APEX1 and PCNA at SSB (Drosophila melanogaster)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Drosophila melanogaster)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
LIG1 bound to APEX1 and PCNA ligates SSB (Drosophila melanogaster)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Drosophila melanogaster)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
POLD,POLE-mediated DNA strand displacement synthesis (Drosophila melanogaster)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] (Drosophila melanogaster)
Rrp1 [nucleoplasm] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P27864
Gene Names
Rrp1
Reference Genes
BioGPS Gene:33500 Rrp1
ENSEMBL:FBgn0004584
Flybase:FBgn0004584
KEGG Gene (Drosophila melanogaster):Dmel_CG3178 Rrp1
Monarch:33500 Rrp1
NCBI Gene:33500 Rrp1
Reference Transcript
RefSeq:NM_057493.4 Rrp1
Other Identifiers
143488_at
1625109_at
33500
GO:0003674
GO:0003677
GO:0003906
GO:0004518
GO:0004519
GO:0004528
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0006259
GO:0006281
GO:0006284
GO:0006950
GO:0006974
GO:0008150
GO:0008311
GO:0008408
GO:0016787
GO:0016829
GO:0019899
GO:0034641
GO:0043167
GO:0043226
GO:0046872
GO:0052720
GO:0070182
GO:0090305
GO:0140078
Participant Of
hasComponent
APEX1:AP-dsDNA [nucleoplasm]
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm]
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm]
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm]
APEX1:SSB(5'-ddRP)-dsDNA [nucleoplasm]
APEX1:SSB(AP->5'-dRP)-dsDNA [nucleoplasm]
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm]
input
Displacement of NTHL1 glycosylase by APEX1 at the AP site
Displacement of OGG1 glycosylase by APEX1 at the AP site
Displacement of SMUG1 glycosylase by APEX1 at the AP site
Displacement of TDG glycosylase by APEX1 at the AP site
Inferred From
APEX1 [nucleoplasm] (Homo sapiens)
Cross References
RefSeq
NP_476841.1
Flybase
FBgn0004584
PRO
P27864
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